Bioadhesive Microspheres Market
Number of pages: 100 | Report Format: PDF | Published date: March 10, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
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Report Attribute |
Details |
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Market Size Value in 2022 |
US$ 1.33 billion |
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Revenue Forecast in 2031 |
US$ 2.96 billion |
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CAGR |
9.23% |
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Base Year for Estimation |
2022 |
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Forecast Period |
2023-2031 |
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Historical Year |
2021 |
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Segments Covered |
Materials, Route of Administration, End-user, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global bioadhesive microspheres market was valued at US$ 1.33 billion in 2022 and is expected to register a revenue CAGR of 9.23% to reach US$ 2.96 billion by 2031.
Bioadhesive Microspheres Market Fundamentals
Microspheres are small, spherical particles with diameters ranging from 1 to 1,000 microns. They are made from various materials, such as polymers, metals, ceramics, and glass, and can be designed with specific physical and chemical properties depending on their intended application. Microspheres can be produced using various methods, including emulsification, solvent evaporation, spray drying, and microfluidics. Mucoadhesive and bioadhesive microspheres are types of microspheres used in drug delivery applications.
Bioadhesive microspheres are tiny particles of biodegradable polymers that can adhere to biological tissues. These microspheres are designed for drug delivery, as they can be loaded with drugs and targeted to specific sites in the body. These microspheres’ bioadhesive properties help increase drug retention at the target site, thereby enhancing drug efficacy and reducing side effects. Bioadhesive microspheres can be administered via various routes, including oral, nasal, vaginal, and colorectal. Using bioadhesive microspheres as drug delivery vehicles has several advantages, such as improved bioavailability, sustained drug release, and reduced dosing frequency. Additionally, these microspheres can protect drugs from degradation, improve drug solubility, and enhance drug stability. Several techniques are available to prepare bioadhesive microspheres, including emulsion solvent evaporation, coacervation, spray drying, and electrostatic spinning. The choice of technique depends on the specific application and the desired properties of the microspheres.
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Bioadhesive Microspheres Market Dynamics
Chronic diseases such as cancer, diabetes, and cardiovascular diseases are rising globally. Bioadhesive microspheres are used to deliver drugs to treat these diseases. The increasing prevalence of such diseases drives the revenue growth of the global bioadhesive microspheres market. For instance, according to the WHO’s September 2022 factsheet, the prevalence of diabetes across the globe is rising more rapidly in low- and middle-income countries than in high-income countries. Diabetes patients rose from 108 million to 422 million from 1980 to 2014. Pharmaceutical companies are investing heavily in research & development to develop new and improved drug delivery systems in which bioadhesive microspheres play a vital role. This is further boosting the revenue growth of the global bioadhesive microspheres market. Moreover, government organizations around the globe are taking initiatives to promote healthcare and improve access to healthcare facilities. This fuels the demand for new and improved drug delivery systems, including bioadhesive microspheres, which can improve efficacy and affordability.
However, bioadhesive microspheres are a relatively new technology, and there may be limited awareness among healthcare professionals and patients about their benefits and applications. This can limit the adoption of bioadhesive microspheres and restrict market revenue growth. Moreover, developing bioadhesive microspheres requires significant investment in research and development. The high development costs may deter smaller pharmaceutical companies from investing in this technology, limiting market revenue growth. Additionally, the availability of alternative drug delivery systems and complex manufacturing processes are some of the restraints impeding the bioadhesive microspheres market revenue growth.
Bioadhesive Microspheres Market Ecosystem
The global bioadhesive microspheres market is analyzed from four perspectives: materials, route of administration, end-user, and region.
Bioadhesive Microspheres Market by Materials
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Based on the materials, the global bioadhesive microspheres market is segmented into natural polymer and synthetic polymer.
The natural polymer segment dominated the market with the principal revenue share in 2022, attributed to its biocompatibility, biodegradability, and ease of availability. Natural polymers are often biocompatible and biodegradable, making them less likely to cause adverse reactions or harm live tissues. This makes them suitable for medical and pharmaceutical applications. They are derived from renewable resources, such as plant or animal sources, making them a more sustainable alternative to synthetic polymers derived from petrochemicals. Some common examples of natural polymers used in bioadhesive microspheres are chitosan, alginate, gelatin, starch, and hyaluronic acid. Chitosan is a natural polymer derived from chitin, a substance found in the shells of crustaceans. Chitosan has excellent mucoadhesive properties and is biocompatible, making it a popular choice for drug delivery systems.
Natural polymers can be used in various applications, such as drug delivery, wound healing, and tissue engineering. This versatility makes them valuable tools in many different industries. These advantages contribute to the revenue growth of the natural polymer segment.
The synthetic polymer segment dominated the market with the second-largest revenue share in 2022, owing to their advantages, such as improved drug delivery, biodegradability, and better control over drug release kinetics. Polyethylene glycol, poly lactic-co-glycolic acid, polyvinyl alcohol, polyacrylic acid, and polysaccharides are some examples of synthetic polymers widely used in bioadhesive microspheres. Synthetic polymers can be tailored to release drugs at a specific rate or in response to certain triggers, such as changes in pH or temperature. This can improve the efficacy and safety of drugs by ensuring that they are delivered in the appropriate amount and at the right time. Additionally, synthetic polymers can be produced in large quantities and with high purity, reducing costs and ensuring consistency in product quality. Synthetic polymers can be designed to have specific properties, such as mucoadhesive properties or the ability to cross biological barriers. This can improve drug delivery to specific tissues or organs. These factors contribute to the growth of the synthetic polymer segment.
Bioadhesive Microspheres Market by Route of Administration
Based on the route of administration, the global bioadhesive microspheres market is segmented into oral, nasal, ocular, colorectal, and others.
The oral route segment dominated the market with the largest revenue share in 2022, owing to high patient acceptance and the growing prevalence of gastrointestinal health issues. Oral bioadhesive microspheres are designed to adhere to the mucosal surface of the gastrointestinal tract, providing targeted drug delivery for various diseases and conditions. The oral route of drug administration is the most common and preferred route of administration among patients. Bioadhesive microspheres offer an additional advantage of targeted drug delivery, making them an attractive option for patients.
Bioadhesive Microspheres Market by End-user
Based on the end-user, the global bioadhesive microspheres market is segmented into hospitals & clinics, academic & research institutes, pharmaceutical & biotechnology industries, and others.
The pharmaceutical & biotechnology industries segment dominated the bioadhesive microspheres market with the largest revenue share in 2022, owing to rising drug discovery-related activities. Bioadhesive microspheres can be used to deliver drugs to treat these diseases, thereby driving segment revenue growth. With the growing demand for more effective and targeted drug delivery systems, the pharmaceutical and biotechnology industries are increasingly turning to bioadhesive microspheres as a promising solution. Bioadhesive microspheres can provide sustained-release formulations of drugs, improving patient compliance and convenience. This is particularly important for drugs requiring prolonged administration or a narrow therapeutic window. The pharmaceutical and biotechnology industries are investing heavily in the research and development of advanced drug delivery systems, including bioadhesive microspheres. Advancements in technology have enabled the development of more efficient and targeted drug delivery systems, which are driving segment revenue growth.
Bioadhesive Microspheres Market by Region
Geographically, the global bioadhesive microspheres market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America dominated the global bioadhesive microspheres market with the largest revenue share in 2022, attributed to growing awareness and high adoption of novel microspheres used as drug delivery systems. Additionally, companies across the region are continuously involved in launching new and novel medications using the microsphere, which is also helping in the revenue growth of the market.
Bioadhesive Microspheres Market Competitive Landscape
The prominent players operating in the global bioadhesive microspheres market are:
Bioadhesive Microspheres Market Strategic Developments
Bioadhesive microspheres are tiny particles composed of biodegradable polymers that can adhere to biological tissues.
The global bioadhesive microspheres market is estimated to be valued at US$ 2.96 billion by 2031.
The bioadhesive microspheres market is expected to be valued at a revenue CAGR of 9.23% from 2023 to 2031.
The availability of alternative drug delivery systems and complex manufacturing processes restrict global market revenue growth to its full potential.
Some prominent players operating in the global bioadhesive microspheres market are Intrexon Corporation, 3M Company, Takeda Pharmaceutical Company Limited, Merck KGaA, and BioDelivery Sciences International, Inc.
*Insights on financial performance are subject to the availability of information in the public domain