Number of pages: 100 | Report Format: PDF | Published date: July 25, 2022
Historical Years – 2020 | Base Year – 2021 | Forecasted Years – 2022-2030
Report Attribute |
Details |
Market size value in 2021 |
US$ 2.88 billion |
Revenue forecast in 2030 |
US$ 7.59 billion |
Growth Rate |
CAGR of 11.4% from 2022 to 2030 |
Base year for estimation |
2021 |
Forecast period |
2022-2030 |
Segments covered |
Type, Products, Application |
Regional scope |
North America, Europe, Asia Pacific, and the Rest of the World (ROW) |
The global protein expression market was pegged at US$ 2.88 billion in 2021 and is expected to witness a CAGR of 11.4% during the forecast period.
Market Fundamentals
Protein expression is defined as the process by which amino acids or proteins are produced within the cells of living organisms. Translation, transcription, and post-translational modification are the three processes involved in protein expression. It includes a variety of expression systems derived from bacterial, algal, insect, cell-free, yeast, and mammalian cells. Protein expression is a technique commonly used to investigate the presence of one or more proteins in tissues or cells, and bears several advantages, including high expression, good stability, fast breeding, strong anti-pollution ability, and ease of product purification.
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Market Dynamics
Increased R&D investment by biotechnology and pharmaceutical companies is a major factor driving the growth of the global protein expression market. The availability of new and advanced technologies to meet the needs of drug and biologics product manufacturers encourages the use of protein expression products for research and manufacturing.
Market Ecosystem
The global protein expression market has been analyzed from five perspectives by type, products, application, end user and region.
Protein Expression Market by Type
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Based on type, the global protein expression market has been segmented into e. coli, mammalian, yeast, cell free, and others. During the forecast period, cell-free expression is expected to hold a significant market share in the protein expression market. Because of its widespread acceptance, cell-free protein expression is well-established approach in the market. This technique has many advantages over other protein expression techniques, and thus is widely used in several life sciences applications. Some of such benefits of cell-free protein techniques include increased speed, the ability to express toxic proteins, and the ease of amino acid type selective labelling, among others.
Protein Expression Market by Products
Based on products, the global protein expression market has been segmented into reagents, expression vectors, competent cells, instruments, and services. The reagents segment dominated the global market. Furthermore, the reagents segment is also expected to grow at the fastest rate in the market during the forecast period. The significant use of reagents in a synthetic examination of cell/tissue present in the human body is one of the key factors driving global market growth. Moreover, reagents are used extensively during the protein expression process in various forms such as acids and bases, and they have numerous applications in research, industry production, and pharmaceutical production. Hence, due to the incumbent usage of reagents across various stages of protein expression, the market for this segment is expected to grow exponentially.
Protein Expression Market by Application
Based on application, the global protein expression market has been segmented into therapeutic, industrial, and research. The therapeutic segment held the largest market share, and it is expected to grow at the fastest rate during the forecast period. The therapeutic use of protein expression processes is done to influence the course of conditions, syndromes, diseases, or pathology in order to benefit the patient's health. Protein expression therapy can thus be used to derive treatments for a wide range of chronic diseases and genetic mutations, including cancer, cystic fibrosis, heart disease, diabetes, haemophilia, and AIDS, and has shown promising results in patients suffering from such diseases.
Protein Expression Market by End User
Based on end user, the global protein expression market has been segmented into pharmaceuticals & biotechnology companies, academic research institutes, contract research organizations and others. The pharmaceutical and biotechnology companies segment generated the highest revenue during forecast period. Furthermore, the segment is expected to have the highest CAGR during the forecast period. The significant use of reagents in synthetic examination of cell/tissue present in the human body is one of the key factors driving the global market growth.
Protein Expression Market by Region
Based on the region, the global protein expression market has been segmented into North America, Europe, Asia Pacific, and the Rest of the World. North America dominated the global protein expression market segment during the forecast period. However, Asia Pacific is not far behind, and it is expected to grow rapidly. Heavy investments in the medical sector, rapid growth in technological innovation, and an economic boom could all help the Asia Pacific protein expression market grow. Furthermore, the rise life sciences and healthcare expenditure has created a need for technological advancement in the Asia Pacific market. The majority of investments are observed to be coming from countries such as China, Japan, and India, which are developing at a rapid pace; and yearly medical investment is increasing at the same time, assisting firms, educational institutes, and researchers to study protein expression and develop the best possible outcomes. In addition, one positive trend in the Asia Pacific market indicates that this region is highly cost sensitive, which has proven to be a great opportunity for the introducing innovative cost-saving approaches.
Competitive Landscape
Some prominent players in the global protein expression market are
Strategic Developments
Government regulations requiring biologics to undergo rigorous preclinical and clinical trials prior to regulatory approval, as well as the time-consuming process for biologic approval are limiting the market growth.
Rising prevalence of chronic diseases, particularly among the geriatric population, increasing funding for research activities and technological advancement in the past few years are the prime reason driving growth of the market.
Some prominent players in the global protein expression market are Bio Rad Laboratories Inc., Agilent Technologies Inc., Thermo Fisher Scientific Inc., Merck KGaA among others.
The reagents segment dominated the global protein expression market during forecast period.
North America is expected to dominate the overall protein expression market due to factors such as well-established healthcare infrastructure in the region, as well as intense R&D activities.
*Insights on financial permanence is subject to availability of information in public domain