Number of pages: 100 | Report Format: PDF | Published date: April 13, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
Report Attribute |
Details |
Market Size Value in 2022 |
US$ 459.85 million |
Market Size Value in 2031 |
US$ 863.84 million |
CAGR |
8.2% |
Base Year For Estimation |
2022 |
Forecast Period |
2023 to 2031 |
Historical Year |
2021 |
Segments Covered |
Diagnosis and Treatment, Route of Administration, Distribution Channel, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global pemphigus vulgaris market was valued at US$ 459.85 million in 2022 and is expected to register a revenue CAGR of 8.2% to reach US$ 863.84 million by 2031.
Pemphigus Vulgaris Market Fundamentals
The pemphigus vulgaris is a rare autoimmune disorder that affects the skin and mucous membranes. The formation of painful blisters and sores on the skin, mouth, throat, nose, genitals, and anus characterizes it. Pemphigus vulgaris occurs when the immune system mistakenly attacks healthy cells in the body, particularly the proteins that hold skin cells together. This leads to the separation of skin layers and the formation of blisters. Pemphigus vulgaris is typically treated with immunosuppressive drugs, corticosteroids, and biological therapies to manage symptoms and prevent complications. It is important to seek medical attention if you are experiencing symptoms of pemphigus vulgaris to receive prompt diagnosis and treatment.
The pemphigus vulgaris market outlook is positive and is expected to grow during the forecast period, driven by factors such as an increasing prevalence of autoimmune diseases, rising healthcare expenditure, and ongoing research and development efforts. The market is also expected to benefit from the approval of new therapies, which will offer patients more treatment options and improve the standard of care for this condition.
However, the pemphigus vulgaris market also faces several challenges, including the high cost of treatment, the limited patient population, and the potential for serious side effects associated with current therapies. In addition, there is a need for greater awareness of pemphigus vulgaris among healthcare providers and the general public, which could help improve patient diagnosis and treatment outcomes.
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Pemphigus Vulgaris Market Dynamics
The global prevalence of pemphigus vulgaris is increasing, driving the pemphigus vulgaris market revenue growth. This is attributed to various factors such as changes in lifestyle, environmental factors, and genetic predisposition. According to the International Pemphigus & Pemphigoid Foundation, pemphigus vulgaris occurs approximately between 0.1 and 2.7 per 100,000 people per year globally. There is a growing focus on research and development of new treatment options for pemphigus vulgaris, including new diagnostic tools, targeted therapies, and personalized medicine approaches. Biologic therapies are becoming increasingly popular in treating pemphigus vulgaris due to their efficacy and fewer side effects compared to other treatment options. This has led to increased market research and the development of biological therapies.
There is a growing awareness of Pemphigus vulgaris among healthcare providers, leading to earlier diagnosis and prompt treatment. This is expected to fuel the pemphigus vulgaris market revenue growth as more patients seek medical attention. Developing new diagnostic tools and treatment options is another trend observed in the pemphigus vulgaris market. This includes using advanced diagnostic techniques such as ELISA and immunofluorescence and developing targeted therapies. However, the high cost of treatment is restricting the pemphigus vulgaris market growth.
Pemphigus Vulgaris Market Ecosystem
The global pemphigus vulgaris market is analyzed from four perspectives: diagnosis and treatment, route of administration, distribution channel, and region.
Pemphigus Vulgaris Market by Diagnosis and Treatment
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Based on the diagnosis, the global pemphigus vulgaris market is segmented into histopathology, direct immunofluorescence, indirect immunofluorescence, and others.
Direct immunofluorescence is a highly accurate diagnostic method for Pemphigus Vulgaris, with a sensitivity of up to 95% and a specificity of up to 100%. This makes direct immunofluorescence segment an ideal method for confirming the diagnosis of pemphigus vulgaris and distinguishing it from other blistering disorders. Direct immunofluorescence has been used for many years to diagnose pemphigus vulgaris and is a well-established method widely used by healthcare providers, particularly dermatologists and pathologists. This has contributed to its dominance in the pemphigus vulgaris market. Direct immunofluorescence is a relatively simple and cost-effective diagnostic method that can be performed in most clinical laboratories. This has made it accessible to a wide range of healthcare providers and has contributed to its widespread use. Accurately diagnosing pemphigus vulgaris is crucial for initiating appropriate treatment, which can help control symptoms and prevent complications. Direct immunofluorescence plays a key role in this process, making it an important diagnostic method in the pemphigus vulgaris market.
Based on the treatment, the global pemphigus vulgaris market is segmented into corticosteroids, immunosuppressive, biological therapies, intravenous immunoglobulin (IVIG) therapy, and others.
The corticosteroids segment is highly effective in controlling the symptoms of pemphigus vulgaris by suppressing the immune response and reducing inflammation. They are the most widely used and effective treatment options for this disease. Corticosteroids have been used for many years to treat pemphigus vulgaris and are a well-established treatment option that healthcare providers widely use. This has contributed to their dominance in the pemphigus vulgaris market. Corticosteroids are relatively inexpensive and widely available, making them an accessible treatment option for patients with pemphigus vulgaris, thus boosting segmental growth. Corticosteroids are often combined with immunosuppressive drugs to enhance their efficacy and reduce the risk of side effects. This has contributed to their widespread use and dominance in the pemphigus vulgaris market. Although other treatment options are available for pemphigus vulgaris, such as immunosuppressive drugs, these treatments are often used with corticosteroids rather than as a stand-alone treatment. This has contributed to the dominance of the corticosteroid segment in the pemphigus vulgaris market.
The biological therapies segment is expected to experience lucrative revenue growth during the forecast period. Biological therapies target specific molecules or cells involved in the disease process, improving efficacy and reducing side effects compared to traditional non-biological therapies. Biological therapies offer a novel mechanism of action that may be more effective and better tolerated than existing therapies. While corticosteroids and immunosuppressive drugs are the current standard of care for pemphigus vulgaris, they have limitations in terms of efficacy and safety. Therefore, a significant unmet need for more effective and safer therapies has led to increased interest and investment in developing novel biological therapies. Several promising biological therapies for pemphigus vulgaris are currently in clinical trials, and early results have been encouraging, which is also expected to fuel segmental revenue growth.
Pemphigus Vulgaris Market by Route of Administration
Based on the route of administration, the global pemphigus vulgaris market is segmented into oral, parenteral, and others.
The oral segment had a prominent pemphigus vulgaris market revenue share in 2022. Oral medications, such as corticosteroids and immunosuppressive drugs, are the first-line treatment for pemphigus vulgaris and are typically administered orally. Oral medications have been used for many years to treat pemphigus vulgaris and are a well-established treatment option that healthcare providers widely use. This has contributed to their dominance in the market. Oral medications are convenient, easy to administer, and do not require specialized equipment or medical personnel. This is particularly important for chronic conditions like pemphigus vulgaris, where patients may need to take medications for an extended period. Many patients prefer oral medications over other routes of administration, such as injections or infusions, due to their convenience and ease of use. While other administration routes are available for some medications used to treat pemphigus vulgaris, such as intravenous or subcutaneous injection, these are often reserved for patients who cannot take medications orally. Therefore, the oral route of administration is the most common and dominant route for treating pemphigus vulgaris.
Pemphigus Vulgaris Market by Distribution Channel
Based on the distribution channel, the global pemphigus vulgaris market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies.
The hospital pharmacies segment dominated the pemphigus vulgaris market with the largest revenue share. Pemphigus vulgaris is a rare autoimmune disease requiring specialized care and treatment, often provided in hospitals. Patients with severe or refractory disease may require hospitalization, which increases the demand for medications from hospital pharmacies. Many medicines used to treat pemphigus vulgaris, such as corticosteroids and immunosuppressive drugs, require close monitoring and dosage adjustments, which hospital pharmacists often manage. In addition, hospital pharmacists are responsible for dispensing medications to inpatients, which can drive demand for medications from hospital pharmacies. Some medications used to treat pemphigus vulgaris, such as biological therapies, may only be available through hospital pharmacies due to their specialized nature and complex administration requirements. This can drive demand for medications from hospital pharmacies. Hospital pharmacists often work closely with healthcare providers, including dermatologists and rheumatologists, responsible for managing pemphigus vulgaris. This collaboration can improve medication adherence and patient outcomes, which can drive demand for medications from hospital pharmacies.
Pemphigus Vulgaris Market by Region
Geographically, the global pemphigus vulgaris market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America has the largest pemphigus vulgaris market size in terms of revenue generation. North America has some of the most advanced healthcare facilities in the world, including specialized dermatology and rheumatology clinics, which are equipped to manage pemphigus vulgaris. This has improved access to care and increased demand for medications. The incidence of pemphigus vulgaris is increasing in North America, fueling the demand for medications and treatments. There have been significant advancements in diagnosing and treating pemphigus vulgaris in North America, improving patient outcomes and increasing demand for medications. The pharmaceutical market in North America is strong and well-developed, which has led to the development of new and innovative drugs and treatments for pemphigus vulgaris.
Competitive Landscape of the Global Pemphigus Vulgaris Market
The prominent players operating in the global pemphigus vulgaris market are:
Strategic Developments in the Pemphigus Vulgaris Market
The expected size of the global pemphigus vulgaris market in 2031 is US$ 863.84 million.
North America accounts for the largest market revenue share, followed by Europe, and Asia Pacific is expected to be the fastest-growing region during the forecast period.
The prominent players operating in the global pemphigus vulgaris market are Novartis AG, Pfizer Inc., F. Hoffmann-La Roche Ltd, Genentech, Inc., GlaxoSmithKline plc, and Alexion Pharmaceuticals, Inc. (AstraZeneca).
During the forecast period, the revenue CAGR of the global pemphigus vulgaris market is expected to be 8.2%.
The corticosteroids segment dominates the global pemphigus vulgaris market with the largest revenue share.
*Insights on financial performance are subject to the availability of information in the public domain