NGS Automation Market
Number of pages: 100 | Report Format: PDF | Published date: April 19, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
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Report Attribute |
Details |
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Market Size Value in 2022 |
US$ 426.67 million |
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Market Size Value in 2031 |
US$ 1,469.1 million |
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CAGR |
13.0% |
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Base Year For Estimation |
2022 |
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Forecast Period |
2023 to 2031 |
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Historical Year |
2021 |
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Segments Covered |
Product, Application, End User, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global NGS automation market was valued at US$ 426.67 million in 2022 and is expected to register a revenue CAGR of 13.0% to reach US$ 1,469.1 million by 2031.
NGS Automation Market Fundamentals
Next-generation sequencing (NGS) is becoming increasingly significant in understanding and treating illness. As a result, effective NGS library preparation is more important than ever, as poor-quality libraries seldom give dependable, high-quality findings. However, library preparation methods are often time-consuming and labor-intensive, requiring dozens, if not hundreds, of steps to prepare DNA or RNA samples for sequencing.
Next-generation sequencing (NGS) has grown in popularity in clinical laboratories and is an important tool in many patients’ diagnostic journeys. Additionally, converting native DNA to a barcoded library detectable by NGS is a highly technical procedure that requires substantial time and chemicals while also being error-prone. This barrier might force many laboratories to rely on send-out services for their NGS testing. Dedicated automation technologies for NGS library preparation, including liquid handling equipment and integrated microfluidic systems, save time and money while decreasing errors.
The procedure leading to automated NGS sequencing has two major components, both of which can be automated. The first step is sample preparation, which entails chemically or physically breaking cells in the collected tissue (e.g., blood, saliva) to liberate DNA from within the nucleus, then isolating the DNA into a highly pure and concentrated solution. The second phase of library preparation entails several repetitious and delicate tasks. The fragmented DNA is ligated to adapters that identify the sample and bind the hybridized DNA adapter to a solid state for amplification and sequencing.
Even little mistakes might cost hundreds to thousands of dollars in reagents and consumables. The danger of these sorts of mistakes is reduced by creating an automated process that preprograms them into an instrument built to perform repeated operations reliably. Furthermore, many automated methods provide error reporting, allowing scientists to remedy the problem or stop the process from reducing reagents and supply waste if an error cannot be repaired.
Although automation’s cost and time saving depend on an individual laboratory’s throughput, the benefits of automating NGS library preparation can be substantial. Clinical genetics laboratories stand to profit considerably from the use of this technology by lowering costs, time, and loss due to mistakes.
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NGS Automation Market Dynamics
The expanding R&D activities in the life sciences sector, the growing need for NGS automation in laboratories, and the rising frequency of chronic illnesses such as cancer are driving the expansion of market revenue. Furthermore, the growing number of partnerships between firms to create library preparation procedures and the increasing applications of next-generation sequencing will likely present considerable potential prospects for this market revenue.
NGS involves several processes, including sample preparation, library preparation, sequencing, and bioinformatics. Library preparation includes several repeated processes that need the precise pipetting of small sample amounts. This technique is particularly susceptible to human mistakes, jeopardizing the entire NGS process. Library preparation automation can improve lab productivity and produce more reliable findings. NGS automation also contributes to shorter turnaround times and higher sample throughput. Apart from medical services, companies in the NGS automation market are expanding their income streams by pursuing incremental potential in agricultural and animal research. This is obvious, given that the market revenue is expected to grow at an astounding CAGR during the forecast period.
NGS is transforming agricultural production while also assisting in evaluating its function in human health, gut, air, water, and soil microbiomes. Companies in the NGS sample preparation industry are investing more in discovering novel disease genes in animals with multigenic diseases. NGS is also assisting in tracing the origins of plant illnesses and recommending solutions to eradicate them.
The COVID-19 pandemic has influenced the NGS sample preparation sector. The rising number of coronavirus infections globally necessitated the development of efficient and rapid sequencing methods to reconstruct the genomic sequence of SARS-CoV-2, the etiological agent of COVID-19. It was essential in developing diagnostic molecular tests and efficient tactics and plans to prevent the spread of the pandemic.
However, the high cost of automation workstations will stymie NGS automation solution adoption and limit the market’s revenue growth. The regulatory and standardization problems in diagnostic testing and the need for highly experienced employees to operate automation software are important hurdles to the market’s revenue growth.
NGS Automation Market Ecosystem
The global NGS automation market is analyzed from four perspectives: product, application, end-user, and region.
NGS Automation Market by Product
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Based on product, the global NGS automation market is segmented into workstation/robotic platforms and reagents & consumables.
The workstation/robotic platform segment will account for most of the NGS automation market during the forecast period. The substantial proportion of this sector may be ascribed to reasons such as the rising demand for NGS automation solutions in laboratories and the advantages of NGS automation during library preparation over manual operations.
NGS Automation Market by Application
Based on application, the global NGS automation market is segmented into drug discovery, clinical diagnostics, and others. Clinical diagnostics is further sub-segmented into oncology, infectious diseases, reproductive health, and other clinical diagnostics.
The clinical diagnostic segment is expected to register the fastest revenue CAGR during the forecast period. This segment’s rapid revenue expansion may be ascribed to diagnostic laboratories’ increased use of NGS to improve their skills in identifying uncommon genetic disorders, performing genomic profiling for precision oncology, and detecting pathogens in infectious illnesses.
NGS Automation Market by End User
Based on end-user, the global NGS automation market is segmented into hospitals & diagnostic laboratories, pharmaceutical and biotechnology companies, academic research institutes, and others.
The pharmaceutical & biotechnology companies segment is expected to dominate this market with the largest revenue share. The growing R&D expenditures of pharmaceutical and biotechnology businesses and the expanding need for new medication research and discovery account for a substantial part of this market. Furthermore, the ability of pharmaceutical and biotechnology corporations to obtain extremely powerful NGS automation workstations drives the expansion of market revenue.
NGS Automation Market by Region
Based on region, the global NGS automation market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America is expected to account for the highest revenue share of the NGS automation market, followed by Europe, Asia Pacific, Latin America, and the Middle East and Africa. An adequate healthcare system availability helps boost NGS automation market adoption chances in the United States. The use of NGS by large clinical laboratories to research sickness genesis and epidemiology has grown to use various automated sample preparation products. Technological improvements, more product approvals and launches, partnerships, and collaborations among major companies drive revenue growth in the NGS automation market. For instance, in February 2021, QIAGEN and INOVIO expanded their collaboration to develop a companion diagnostic for INOVIO’s VGX-3100 for advanced cervical dysplasia utilizing next-generation sequencing (NGS). Furthermore, Guardant Health Inc. gained FDA clearance for Guardant360 CDx in August 2020, which employs two combination technologies, liquid biopsy and NGS, in a single diagnostic test. As a result, growing product approval for NGS diagnostics and product launches may generate new possibilities for the industry, resulting in significant segment revenue growth during the forecast period. The top market players’ rising technological innovation, product launches, collaborations, and acquisitions drive market revenue expansion in North America. For instance, Illumina Inc. and Nashville Biosciences LLC, a Vanderbilt University Medical Centre (VUMC) subsidiary, signed a multi-year agreement in January 2022 to accelerate medicine development through large-scale genomics and the establishment of a clinical-genomic resource using Illumina’s next-generation sequencing (NGS) platforms.
During the forecast period, Asia Pacific is expected to be the fastest-growing market in terms of revenue share. Because of the region’s improved healthcare infrastructure, Asia-Pacific is becoming an increasingly appealing market for healthcare product makers and service providers. The rising population is the primary driver of this region’s healthcare and pharmaceutical sectors, attracting significant investment from private and governmental entities and resulting in high prices.
NGS Automation Market Competitive Landscape
The NGS automation market is slightly concentrated due to the existence of a few companies operating globally as well as regionally. The prominent market players operating in the global NGS automation market include,
NGS Automation Market Strategic Development
Next-generation sequencing (NGS) is becoming increasingly significant in understanding and treating illness. As a result, effective NGS library preparation is more important than ever, as poor-quality libraries seldom give dependable, high-quality findings.
Asia Pacific is the key growth region in the global NGS automation global market.
The prime driving factors in the global automation market are expanding R&D activities in the life sciences sector and the rising frequency of chronic illnesses.
The prominent market players operating in the global NGS automation market include Agilent Technologies, Inc., Danaher Corporation, and Hamilton Company.
The clinical diagnostics segment leads the global NGS automation market.
*Insights on financial performance are subject to the availability of information in the public domain