Liposome Drug Delivery Market
Number of pages: 100 | Report Format: PDF | Published date: June 06, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023 to 2031
|
Report Attribute |
Details |
|
Market Size Value in 2022 |
US$ 4.92 billion |
|
Revenue Forecast in 2031 |
US$ 10.60 billion |
|
CAGR |
8.90% |
|
Base Year for Estimation |
2022 |
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Forecast Period |
2023 to 2031 |
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Historical Year |
2021 |
|
Segments Covered |
Product, Technology, Application, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global liposome drug delivery market was valued at US$ 4.92 billion in 2022 and is expected to register a revenue CAGR of 8.90% to reach US$ 10.60 billion by 2031.
Liposome Drug Delivery Market Fundamentals
Liposome drug delivery is a technique that involves using liposomes, which are small vesicles composed of lipid bilayers, to deliver therapeutic agents to specific targets in the body. Liposomes have gained significant attention in the field of drug delivery due to their unique properties that allow for enhanced drug efficacy, improved bioavailability, and reduced toxicity. The drug molecules can be either hydrophilic (water-soluble) or hydrophobic (fat-soluble), allowing liposomes to accommodate a wide range of therapeutic agents.
The liposomal drug delivery system offers several advantages over conventional drug delivery methods. Liposomes can protect the encapsulated drugs from degradation, metabolism, and elimination in the body, thereby prolonging their circulation time and enhancing their stability. This protection helps to maintain the therapeutic concentration of drugs at the target site for a longer duration.
There are several current trends and emerging opportunities in liposome drug delivery that hold great potential for advancing therapeutic outcomes. Liposomes offer a versatile platform for combination therapies, where multiple drugs or therapeutic agents can be encapsulated within the same liposomal formulation. This allows for synergistic effects and improved treatment outcomes by targeting multiple pathways or simultaneously addressing different aspects of a disease. Combination therapies utilizing liposomes have shown promise in cancer treatment, infectious diseases, and other complex conditions.
Moreover, liposomes have shown potential as vectors for gene delivery, known as lipoplexes or lipid nanoparticles. They can efficiently encapsulate and protect nucleic acids, such as DNA or RNA, and facilitate their targeted delivery into cells. Liposomal gene delivery holds promise for gene therapy, genetic disorders, and personalized medicine, where specific genes can be targeted and modified to treat inherited diseases or restore normal cellular functions.
Liposome Drug Delivery Market Dynamics
In recent years, liposome drug delivery system has gained popularity in treating breast cancer. The drug delivery system offers stable formulation, enhanced pharmacokinetics, and a certain level of passive or physiological targeting of tumor tissue. The rising trends of breast cancer are anticipated to increase the demand for liposome drug delivery. The American Society of Cancer Organization predicts that in 2023, approximately 297,790 women in the United States will receive a diagnosis of invasive breast cancer, while 55,720 women will be diagnosed with non-invasive (in situ) breast cancer.
Significant advancements have been made in liposome technology, leading to improved drug encapsulation, stability, and release characteristics. These advancements have enabled the development of more sophisticated and efficient liposomal formulations, expanding their application in various therapeutic areas. For instance, liposomal formulations have shown great promise in targeting specific cancer cells and tissues while minimizing toxicity to healthy cells. This has led to the development of liposomal chemotherapy drugs such as Doxil and Myocet, which have improved efficacy and reduced side effects compared to traditional chemotherapy.
Pharmaceutical and biotechnology companies are investing heavily in research and development activities to enhance the therapeutic potential of liposome drug delivery systems. The ongoing research efforts are focused on improving drug loading capacity, optimizing release profiles, and developing innovative liposomal formulations, which are expected to drive market revenue growth. Several prominent market players have announced exciting new collaborations leading to the development of innovative products. For instance, Pfizer Inc. and Acuitas Therapeutics signed a development and option agreement in January 2022. This agreement grants Pfizer the option to license Acuitas' lipid nanoparticle (LNP) technology for the development of up to 10 vaccine or therapeutic targets on a non-exclusive basis.
However, the high expense of developing the liposome drug delivery method can be a major challenge for the global liposome drug delivery market. This can be especially difficult in underdeveloped nations with low healthcare funding, and less accessibility.
Liposome Drug Delivery Market Ecosystem
The global liposome drug delivery market is analyzed from four perspectives: product, technology, application, and region.
Liposome Drug Delivery Market by Product
Based on the product, the global liposome drug delivery market is segmented into liposomal doxorubicin, liposomal amphotericin B, liposomal paclitaxel, and others.
The liposomal doxorubicin segment accounted for 27% of the global liposome drug delivery market share in 2022. This is due to the high efficacy of liposomal doxorubicin in treating many chronic diseases such as cancer, including breast cancer, ovarian cancer, and multiple myeloma. Liposomal doxorubicin has a longer half-life than conventional doxorubicin, allowing for a higher drug concentration in tumor tissues and reducing the risk of cardiotoxicity. Additionally, the targeted delivery of liposomal doxorubicin to cancer cells minimizes damage to healthy cells, resulting in fewer side effects for patients. These advantages have contributed to the increasing adoption of liposomal doxorubicin in cancer treatment.
Liposome Drug Delivery Market Technology
Based on technology, the global liposome drug delivery market is segmented into non-PEGylated liposome technology, stealth liposome technology, and depofoam liposome technology.
The stealth liposome technology segment is expected to dominate the global liposome drug delivery market. Stealth liposome technology has numerous advantages over traditional liposome technology. Unlike traditional liposomes, stealth liposomes are designed to evade detection by the body's immune system, which often triggers an attack on foreign particles. This enables them to remain in circulation for longer periods, enhancing their ability to deliver drugs to target cells. Furthermore, studies have demonstrated that stealth liposomes can mitigate the toxicity and side effects associated with traditional liposome formulations. The oral segment is expected to increase the Liposome Drug Delivery Market in the forecast years. Oral medications can effectively reduce inflammation and pain associated with psoriatic arthritis but can also have side effects.
Liposome Drug Delivery Market by Application
Based on application, the global liposome drug delivery market is segmented into cancer therapy, fungal diseases, pain management, viral vaccines, and photodynamic therapy.
The cancer therapy segment dominated the global liposome drug delivery market. This is due to the increasing prevalence of cancer worldwide and the high demand for effective treatment options. According to World Health Organization, Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2022, or nearly one in six deaths. The most common cancers resulting in deaths are breast, lung, colon, rectum, and prostate. Liposome drug delivery has emerged as a promising approach in cancer therapy as it offers several advantages over conventional chemotherapy, such as targeted drug delivery, reduced toxicity, and improved efficacy. Liposomes are lipid-based vesicles that can encapsulate a variety of drugs and deliver them directly to cancer cells, thereby minimizing damage to healthy tissues. This has led to the development of several liposome-based cancer drugs that have shown promising results in clinical trials. The FDA has approved Doxil for the treatment of ovarian and breast cancers and has shown improved efficacy and reduced toxicity compared to conventional doxorubicin.
Liposome Drug Delivery Market by Region
Based on the region, the liposome drug delivery market is segmented into North America, Europe, Asia Pacific, Latin America, & the Middle East & Africa.
North America accounted for the majority of the liposome drug delivery market revenue share in 2022. This is majorly attributed to increasing incidences of cancer in the region. In the United States, the American Cancer Society has projected that approximately 1.9 million new cases of cancer and around 609,360 cancer-related deaths will occur in 2022. This emphasizes the importance of early detection and effective treatment in managing chronic diseases. Moreover, the region has well-established healthcare facilities and extensive research efforts.
The Asia Pacific liposome drug delivery market is projected to show a significant growth of 9.2% CAGR in the forecast years. This growth is attributed to the increasing prevalence of chronic diseases and the rising demand for targeted drug delivery systems in treating chronic diseases. Additionally, the presence of a large geriatric population in the region is also driving the demand for liposome drug delivery, as this population is more susceptible to chronic diseases that require long-term treatment. The increasing number of clinical trials for liposome drug delivery is also expected to boost market growth in the coming years.
Liposome Drug Delivery Market Competitive Landscape
Several companies emphasize development tactics, such as new launches, product approvals, and other elements like patents and events. The market saw acquisition, partnership, and cooperation activities as inorganic development tactics. These initiatives have enabled the expansion of future economic business prospects and increased demand for liposome drug delivery in the global liposome drug delivery market.
Some of the prominent companies having the largest revenue share in the global liposome drug delivery market are,
Liposome Drug Delivery Market Strategic Developments
Liposome drug delivery is a technique that involves encapsulating drugs within tiny lipid-based vesicles called liposomes. Additionally, liposome drug delivery has the potential to reduce side effects and increase patient compliance due to its targeted delivery capabilities.
The estimated market size of the liposome drug delivery market in 2031 will be US$ 10.60 billion.
The global liposome drug delivery market has witnessed significant growth in recent years due to increasing research and development and increasing cases of cancer.
The global liposome drug delivery market is expected to register a revenue CAGR of 8.90% in the forecast period from 2023 to 2031.
North America region has dominated the global liposome drug delivery market with the highest revenue share.
*Insights on financial performance are subject to the availability of information in the public domain