Number of pages: 100 | Report Format: PDF | Published date: April 28, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023 to 2031
Report Attribute |
Details |
Market Size Value in 2022 |
US$ 614.7 million |
Revenue Forecast in 2031 |
US$ 2,584.31million |
CAGR |
17.3% |
Base Year for Estimation |
2022 |
Forecast Period |
2023 to 2031 |
Historical Year |
2021 |
Segments Covered |
Adsorption, Application, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global hemoperfusion device was valued at US$ 614.7 million in 2022 and is expected to register a revenue CAGR of 17.3% to reach US$ 2,584.31 million by 2031.
Hemoperfusion Devices Market Fundamentals
Hemoperfusion is an extracorporeal blood purification procedure that involves passing anticoagulated whole blood through a device containing adsorbent particles, often a column. Hemoperfusion, also known as hemadsorption, is a technique used to remove poisons from poisonings and cytokines from septic and inflammatory patients. Novel gadgets can also eliminate an expanding number of diseases and compounds. Although hemoperfusion is excellent at eliminating toxins, it is infrequently utilized in treating poisoning and is one of the few extracorporeal detoxification techniques available.
Whole blood is circulated through a column containing fixed adsorbent particles during hemoperfusion. The porous structure of these particles is engineered to form columns with varying adsorption characteristics. Toxins ranging in molecular weight from 100 to 40,000 Daltons bind to the particles and are eliminated when the blood exits the column. Physical adsorption, regulated by molecule size and lipophilicity, binds via hydrophobic interactions, van der Waals interactions, hydrogen bonding, or ionic attraction. Higher-molecular-weight solutes are less effectively adsorbed.
Adsorbent particles are classified into activated charcoal and resins (such as the hydrocarbon polymer polystyrene). Charcoal is more attracted to water-soluble compounds, whereas resins are more attracted to lipid-soluble ones. Resin columns for hemoperfusion are accessible in Europe but not in the United States, save for an emergency or compassionate usage.
Adsorption is significantly more effective than hemodialysis in certain circumstances, hence the earliest uses of sorbent hemoperfusion in acute patients were in treating chemical intoxication and poisoning. In general, this has been accomplished by using charcoal adsorption or resins. These devices generally include between 100 and 300 g of activated charcoal or between 300 and 650 g of resin. Blood flow rates for effective drug elimination range from 300 to 450 mL/min, with intermittent hemoperfusion lasting 4 hours. Adsorption is significantly more effective than hemodialysis in certain circumstances, hence the earliest uses of sorbent hemoperfusion in acute patients were in treating chemical intoxication and poisoning. In general, this has been accomplished by using charcoal adsorption or resins. These devices generally include between 100 and 300 g of activated charcoal or between 300 and 650 g of resin. Blood flow rates for effective drug elimination range from 300 to 450 mL/min, with intermittent hemoperfusion lasting 4 hours.
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Hemoperfusion Devices Market Dynamics
This market has grown because of developments in dialysis and filtration treatments combined with absorption processes. The hemoperfusion device market is expanding since these devices are used in various important therapies. Blood purification devices are commonly employed to treat renal or organ failure, plasmapheresis, and immunological metabolic diseases. As there is an increase in the prevalence of metabolic and immune disorders such as kidney failure, diabetes, and hypertension, as well as an increasing geriatric population across nations that are extremely vulnerable to kidney diseases, the blood purification equipment market is growing. Various technical improvements related to blood purification techniques eliminate further aid in forming the market during the forecast period.
The increasing number of blood and blood-related illnesses is expected to increase demand for hemoperfusion techniques to eliminate toxic and other waste products from the blood. Furthermore, due to the rising need for hemoperfusion treatment methods, defective kidney function is another factor expected to drive market expansion. Sepsis, for instance, is a disorder that happens when an infection spreads to the body via the bloodstream. According to the WHO, Sepsis affects more than 30 million people yearly, possibly leading to 6 million fatalities, primarily in low and middle-income countries. The rising prevalence of sepsis and other similar illnesses is expected to expand the market.
Hemoperfusion procedures are particularly effective for the rapid and direct elimination of harmful pathogens, and these procedures will be widely embraced around the world. Advances in techniques such as bioseparation , filtration, adsorption, and dialysis are projected to offer a substantial push to develop the blood purification equipment market in the future. Blood purification therapy is employed for three key reasons: plasmapheresis, organ failure life support, and metabolic diseases.
A growing geriatric population means a greater number of patients with acute and chronic renal disorders, as well as cases of kidney failure. This, in turn, assists the market in identifying opportunities for growth throughout the projection period. Increasing public health awareness has also proven to be beneficial to industry growth. Better healthcare and reimbursement facilities also motivate people to use cutting-edge technology procedures.
There needs to be more healthcare facilities in developing and underdeveloped nations to ensure market expansion. As people's health awareness grows, the negative impacts of purifying techniques are being emphasized, impeding market growth. The hefty expense consumers must bear to benefit from these amenities also hinders market expansion.
Hemoperfusion Devices Market Ecosystem
The global hemoperfusion devices market is analyzed from the following perspectives by adsorption, application, and region.
Hemoperfusion Devices Market by Adsorption
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Based on adsorption, the global hemoperfusion devices market is segmented into charcoal hemoperfusion and resin hemoperfusion.
The charcoal hemoperfusion segment is likely to dominate the market during forecast periods. Charcoal hemoperfusion is one of the oldest and most widely utilized adsorbent materials in hemoperfusion therapy. Because of its huge surface area and great ability to adsorption of a wide range of poisons and hazardous chemicals, it is beneficial in treating acute poisoning and other critical care circumstances. Certain resins, such as polystyrene or acrylonitrile-based resins, are also employed in hemoperfusion treatment. These resins have different adsorption qualities than charcoal and may be more successful in eliminating certain poisons or hazardous compounds from circulation.
Hemoperfusion Devices Market by Application
Based on application, the global hemoperfusion devices market is segmented into hepatic failure, autoimmune diseases, intoxications, and others.
The autoimmune diseases segment is likely to dominate the market during forecast periods. The increasing prevalence of acute poisoning cases and chronic renal disorders, as well as the growing need for hemoperfusion devices and consumables in critical care settings, are driving the hemoperfusion market in terms of market size. According to hemoperfusions market estimates, the two most typically utilized applications of hemoperfusions are autoimmune and intoxications. In critical care settings, hemoperfusion treatment is generally used to remove toxins and dangerous compounds from the bloodstream in illnesses such as acute liver failure, autoimmune disorders, and intoxications. Hemoperfusion therapy can also be used to treat sepsis, cytokine storm syndrome, and drug overdose.
Hemoperfusion Devices Market by Region
Based on region, the global hemoperfusion devices market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
The United States and Canada are North America's two most important hemoperfusion markets. The high frequency of chronic kidney disease and acute poisoning cases, as well as a well-established healthcare infrastructure, are some of the important reasons driving the growth of the hemoperfusion market in this region. The FDA granted an emergency use license for a blood purification system to treat patients 18 years of age or older with confirmed Coronavirus Disease 2019 (COVID-19) admitted to the intensive care unit (ICU) with proven or impending respiratory failure. R&D efforts and hospital demand for blood-purifying therapies drive the worldwide market's growth prospects.
CAR-T treatment, which includes filtering a patient's blood to eliminate immune system troops known as T Cells, is a group of experts concentrating on blood purification. The treatment comprises a cancer-targeting gene that is subsequently administered intravenously to the patient.
Western Europe and Eastern Europe are the two halves of the European hemoperfusion market. The bulk of Europe's hemoperfusion market share is held by Western Europe, which includes nations such as Germany, France, and the United Kingdom. The increased incidence of chronic kidney disease and government attempts to strengthen healthcare infrastructure are likely to move this region's hemoperfusion market ahead.
The Asia-Pacific region is expected to have the fastest development in the hemoperfusion market because of the rising frequency of acute poisoning cases and chronic renal illnesses in the area. The region's two major hemoperfusion markets are Japan and China. Rising knowledge among the people in this region regarding advancements in the healthcare sector and the numerous treatment techniques available is expected to be an additional development factor for the market. Furthermore, the market in Europe is expected to develop significantly during the forecast period due to rising healthcare expenditure and the increased need for improved treatment options for various ailments.
Hemoperfusion Devices Market Competitive Landscape
Some of the prominent market players in the global hemoperfusion devices market include,
Hemoperfusion Devices Market Strategic Development
Hemoperfusion is an extracorporeal blood purification procedure that involves passing anticoagulated whole blood through a device containing adsorbent particles, often a column. Hemoperfusion, also known as hemadsorption, is a technique used to remove poisons from poisonings and cytokines from septic and inflammatory patients.
North America is the key growth region in the global hemoperfusion devices market.
The increasing number of blood and blood-related illnesses and technological advancement drive the hemoperfusion devices market.
The charcoal hemoperfusion segment led the global hemoperfusion devices market.
Some of the prominent market players in the global hemoperfusion devices market include Baxter International Inc., B. Braun Melsungen AG, and Jafron Biomedical Co., Ltd.
*Insights on financial performance are subject to the availability of information in the public domain