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Hand-Foot Syndrome Treatment Market

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Hand-Foot Syndrome Treatment Market

Hand-Foot Syndrome Treatment Market by Drug Class (Analgesics, NSAID’s), Distribution Channel (Hospital Pharmacy, Online Pharmacy) – Global Outlook & Forecast 2022-2030

GR - 808890 Category: Pharmaceuticals

Number of pages: 100  |  Report Format: PDF  |  Published date: February 28, 2023

Historical Years – 2020  |  Base Year – 2021  |  Forecasted Years – 2022-2030


Hand-Foot Syndrome Treatment Market Scope

Report Attribute

Details

Growth Rate

6.6%

Base Year for Estimation

2021

Forecast Period

2022-2030

Historical Year

2021

Segments Covered

Drug Class, Distribution Channel, and Region

Regional Scope

North America, Europe, Asia Pacific, and the Rest of the World (RoW)

Report Overview

According to the deep-dive market assessment study by Growth Plus Reports, the global hand-foot syndrome treatment market is expected to register a revenue CAGR of 6.6% during the forecast period of 2022-2030.

Hand-Foot Syndrome Treatment Market Fundamentals

Hand-foot syndrome, also known as palmar-plantar erythrodysesthesia, is a side effect caused by certain cancer treatments, particularly chemotherapy and targeted therapy. It is characterized by redness, swelling, pain, and a tingling or burning sensation in the palms of the hands and soles of the feet. In some cases, blisters or calluses may also develop. Hand-foot syndrome is caused by damage to the small blood vessels in the hands and feet, which can result in the accumulation of chemotherapy drugs or their metabolites in these tissues. The severity of hand-foot syndrome can vary depending on the type of chemotherapy used, the dose and frequency of treatment, and individual patient factors.

Hand-foot syndrome is most commonly associated with certain types of chemotherapy, such as capecitabine, 5-fluorouracil, and liposomal doxorubicin, as well as targeted therapies, such as sorafenib and sunitinib. It can also occur as a side effect of other medications, such as some antibiotics and antivirals. Treatment of hand-foot syndrome focuses on managing the symptoms and reducing the risk of complications. This can include the usage of topical creams and ointments, analgesics, NSAIDs, antihistamines, and cooling gloves and socks. In severe cases, treatment may also include dose reduction or interruption of chemotherapy or targeted therapy or the usage of other medications, such as multi-kinase inhibitors.

Effective measures for the prevention and treatment of hand-foot syndrome include systemic and topical treatments, dose reductions, and switching to other drugs in the same class that is associated with lower rates of hand-foot syndrome. These approaches allow patients to continue cancer treatment while reducing negative impacts on quality of life. Although hand-foot syndrome is a medical condition that, while not life-threatening, can significantly impact patients' quality of life and cause discomfort and functional impairment, particularly in older patients. The incidence of hand-foot syndrome depends on various factors, including the chemotherapeutic drug used, treatment schedule, and duration of treatment. Accurate grading of the severity of hand-foot syndrome is essential in guiding clinical decision-making, such as dose delays, reductions, and other therapeutic management options. The grading systems commonly used for hand-foot syndrome severity include the classifications by the World Health Organization (WHO) and the National Cancer Institute (NCI). The WHO system has four grades of severity, while the NCI system has three.

Hand-Foot Syndrome Treatment Market Dynamics

The rising prevalence of cancer globally is the primary factor driving the global hand-foot syndrome treatment market. For instance, according to the American Cancer Society’s 2022 factsheet, as of January 2022, there were approximately 18.1 million cancer survivors in the United States, and in 2032, this number is expected to increase by 24.4% to reach 22.5 million. The development of new and advanced cancer treatments, such as chemotherapy, targeted therapy, and immunotherapy, has increased the demand opportunities in the global hand-foot syndrome treatment market. Additionally, drug development and delivery system advancements, such as transdermal medication administration and nanotechnology, are bringing novel treatment options for the hand-foot syndrome, which is boosting the global hand-foot syndrome treatments market. Moreover, governments throughout the world are boosting their investment in cancer research and treatment, which is encouraging the development of novel hand-foot syndrome therapies and expanding their availability; thus, helping in the development of the global hand-foot syndrome treatments market.

However, the high cost of treatment, side effects associated with the treatment, lack of awareness, and poor reimbursement policies in emerging nations are some of the factors impeding the global hand-foot syndrome treatment market development.

Hand-Foot Syndrome Treatment Market Ecosystem

The global hand-foot syndrome treatment market is analyzed from three perspectives: drug class, distribution channel, and region.

Hand-Foot Syndrome Treatment Market by Drug Class 

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Based on the drug class, the global hand-foot syndrome treatment market is segmented into analgesics, NSAIDs, antihistamines, multi-kinase inhibitors, and others.

The NSAIDs segment dominated the market with the principal revenue share in 2021, owing to the easy availability of these drugs as over-the-counter medicines. NSAIDs are a class of drugs that reduce inflammation and pain by blocking the activity of enzymes called cyclooxygenases (COX). These medicines are commonly used to manage pain and inflammation associated with hand-foot syndrome, particularly in mild to moderate cases. Commonly used NSAIDs for hand-foot syndrome include aspirin, ibuprofen, and naproxen. These medications are available in both prescription and over-the-counter formulations. NSAIDs can be used alone or in combination with other medications, such as analgesics or antihistamines, to manage hand-foot syndrome symptoms. These factors are expected to boost the NSAIDs segment growth.

Hand-Foot Syndrome Treatment Market by Distribution Channel

Based on the distribution channel, the global hand-foot syndrome treatment market is segmented into hospital pharmacy, retail pharmacy, and online pharmacy.

The hospital pharmacy segment dominated the market with the largest revenue share in 2021, attributed to the high patient footfall. Hospital pharmacies may also play a role in educating healthcare professionals and patients about hand-foot syndrome and its treatments. Hospital pharmacies also play an important role in patient care management, collaborating with other healthcare providers to develop treatment plans and ensure that patients receive comprehensive care. Additionally, hospitals are likely to have strong relationships with pharmaceutical companies and distributors, which can help ensure a steady supply of hand-foot syndrome treatments. Moreover, the hospital pharmacy segment is likely to be concentrated in developed countries, where hospitals are well-established and have strong relationships with pharmaceutical companies. These predominant variables contribute to the hospital pharmacy segment growth.

Hand-Foot Syndrome Treatment Market by Region

Geographically, the global hand-foot syndrome treatment market has been segmented into North America, Europe, Asia Pacific, and the Rest of the World. 

North America dominated the global hand-foot syndrome treatment market with the largest revenue share in 2021, owing to expanding research and development efforts, rising healthcare expenditure, and the presence of key companies. In addition, the availability of advanced medical facilities, favorable reimbursement policies, and the presence of major pharmaceutical companies in the region are contributing to the revenue growth of the market. Moreover, companies across the region are continuously carrying out clinical studies to launch new and novel medications for the treatment of hand-foot syndrome, which is helping in the development of the regional market. 

Hand-Foot Syndrome Treatment Market Competitive Landscape

The prominent players operating in the global hand-foot syndrome treatment market are:

Hand-Foot Syndrome Treatment Market Strategic Developments

  • In January 2023, OnQuality Pharmaceuticals received regulatory approval from China and India for Part 2 of the NOVA-II Phase 2 clinical trial. This study evaluates the effectiveness of OQL011, a topical ointment designed to manage Hand-Foot Skin Reaction (HFSR) in cancer patients who are undergoing anti-cancer treatment with vascular endothelial growth factor receptor (VEGFR) inhibitors. NOVA-II is a randomized, double-blinded, dose-ranging Phase 2 clinical trial that aims to determine the safety and efficacy of OQL011 as a topical ointment in treating VEGFRi-associated HFSR. Key objectives of the study include identifying the optimal dosage for Phase 3, evaluating the safety and efficacy of OQL011, and exploring the pharmacokinetics profile of OQL011 in HFSR patients.

Frequently Asked Questions About This Report

The hand-foot syndrome treatment market is expected to register growth at a revenue CAGR of 6.6% during the forecast period from 2022 to 2030.

The development of new and advanced cancer treatments, the rising prevalence of cancer, and the growing geriatric population are driving the global hand-foot syndrome treatment market revenue growth.

The high cost of treatment, side effects associated with the treatment, lack of awareness, and poor reimbursement policies in emerging nations are restricting global market growth to its full potential.

Sun Pharmaceutical Industries, Inc., Valeant Canada, Oceanside Pharmaceuticals, Baxter International, Inc., and Biogen, Inc. are among the top market players.

Asia Pacific is estimated to experience rapid growth in the market during the projected period.

Table of Content

  1. INTRODUCTION
    1. Market Ecosystem
    2. Timeline Under Consideration
      1. Historical Years – 2020
      2. Base Year – 2021
      3. Forecast Years – 2022 to 2030
    3. Currency Used in the Report
  2. RESEARCH METHODOLOGY
    1. Research Approach
    2. Data Collection Methodology
    3. Data Sources
      1. Secondary Sources 
      2. Primary Sources 
    4. Market Estimation Approach
      1. Bottom Up
      2. Top Down 
    5. Market Forecasting Model
    6. Limitations and Assumptions
  3. PREMIUM INSIGHTS
    1. Current Market Trend (COVID-19 Perspective)
    2. Key Players & Competitive Positioning (2021) 
  4. MARKET DYNAMICS
    1. Drivers
    2. Restraints/Challenges
    3. Opportunities
  5. GLOBAL HAND-FOOT SYNDROME TREATMENT MARKET- ANALYSIS & FORECAST, BY TREATMENT TYPE
    1. Analgesics
    2. NSAIDs
    3. Antihistamines
    4. Multikinase Inhibitors
    5. Others
  6. GLOBAL HAND-FOOT SYNDROME TREATMENT MARKET- ANALYSIS & FORECAST, BY DISTRIBUTION CHANNEL
    1. Hospitals Pharmacy
    2. Retail Pharmacy
    3. Online Pharmacy
  7. GLOBAL HAND-FOOT SYNDROME TREATMENT MARKET- ANALYSIS & FORECAST, BY REGION
    1. North America Hand-Foot Syndrome Treatment Market
      1. North America Hand-Foot Syndrome Treatment Market, by Drug Class
      2. North America Hand-Foot Syndrome Treatment Market, by Distribution Channel
      3. North America Hand-Foot Syndrome Treatment Market, by Country
        1. U.S.
          1. U.S. Hand-Foot Syndrome Treatment Market, by Drug Class
          2. U.S. Hand-Foot Syndrome Treatment Market, by Distribution Channel
        2. Canada
          1. Canada Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Canada Hand-Foot Syndrome Treatment Market, by Distribution Channel
    2. Europe Hand-Foot Syndrome Treatment Market
      1. Europe Hand-Foot Syndrome Treatment Market, by Drug Class
      2. Europe Hand-Foot Syndrome Treatment Market, by Distribution Channel
      3. Europe Hand-Foot Syndrome Treatment Market, by Country/Region
        1. Germany
          1. Germany Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Germany Hand-Foot Syndrome Treatment Market, by Distribution Channel
        2. U.K.
          1. U.K. Hand-Foot Syndrome Treatment Market, by Drug Class
          2. U.K. Hand-Foot Syndrome Treatment Market, by Distribution Channel
        3. France
          1. France Hand-Foot Syndrome Treatment Market, by Drug Class
          2. France Hand-Foot Syndrome Treatment Market, by Distribution Channel
        4. Spain
          1. Spain Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Spain Hand-Foot Syndrome Treatment Market, by Distribution Channel
        5. Italy
          1. Italy Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Italy Hand-Foot Syndrome Treatment Market, by Distribution Channel
        6. Rest of Europe 
          1. Rest of Europe Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Rest of Europe Hand-Foot Syndrome Treatment Market, by Distribution Channel
    3. Asia Pacific Hand-Foot Syndrome Treatment Market
      1. Asia Pacific Hand-Foot Syndrome Treatment Market, by Drug Class
      2. Asia Pacific Hand-Foot Syndrome Treatment Market, by Distribution Channel
      3. Asia Pacific Hand-Foot Syndrome Treatment Market, by Country/Region
        1. China
          1. China Hand-Foot Syndrome Treatment Market, by Drug Class
          2. China Hand-Foot Syndrome Treatment Market, by Distribution Channel
        2. Japan
          1. Japan Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Japan Hand-Foot Syndrome Treatment Market, by Distribution Channel
        3. India
          1. India Hand-Foot Syndrome Treatment Market, by Drug Class
          2. India Hand-Foot Syndrome Treatment Market, by Distribution Channel
        4. South Korea
          1. South Korea Hand-Foot Syndrome Treatment Market, by Drug Class
          2. South Korea Hand-Foot Syndrome Treatment Market, by Distribution Channel
        5. Australia
          1. Australia Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Australia Hand-Foot Syndrome Treatment Market, by Distribution Channel
        6. Rest of Asia Pacific
          1. Rest of Asia Pacific Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Rest of Asia Pacific Hand-Foot Syndrome Treatment Market, by Distribution Channel
    4. Rest of the World Hand-Foot Syndrome Treatment Market
      1. Rest of the World Hand-Foot Syndrome Treatment Market, by Drug Class
      2. Rest of the World Hand-Foot Syndrome Treatment Market, by Distribution Channel
      3. Rest of the World Hand-Foot Syndrome Treatment Market, by Region
        1. Rest of the World Hand-Foot Syndrome Treatment Market, by Drug Class
        2. Rest of the World Hand-Foot Syndrome Treatment Market, by Distribution Channel
        3. Latin America
          1. Latin America Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Latin America Hand-Foot Syndrome Treatment Market, by Distribution Channel
        4. Middle East & Africa
          1. Middle East & Africa Hand-Foot Syndrome Treatment Market, by Drug Class
          2. Middle East & Africa Hand-Foot Syndrome Treatment Market, by Distribution Channel
  8. COMPANY PROFILES         
    1. Sun Pharmaceutical Industries, Inc
      1. Business Snapshot
      2. Products Offered
      3. Financial Details*
      4. Strategic Development
    2. Pfizer Inc.
    3. Eli Lilly and Company
    4. Merck & Co., Inc.
    5. Novartis International AG
    6. Teva Pharmaceutical Industries Ltd.
    7. Eisai Co. Ltd.
    8. GlaxoSmithKline plc
    9. Celgene Corporation
    10. Valeant Canada, 
    11. Oceanside Pharmaceuticals
    12. Baxter International, Inc.
    13. Biogen, Inc.

*Insights on financial performance are subject to availability of information in the public domain

 

List of Tables

 

  1. Global Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million)
  2. Global Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  3. Global Hand-Foot Syndrome Treatment Market, By Region, 2020-2030 (US$ Million) 
  4. North America Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  5. North America Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million)
  6. North America Hand-Foot Syndrome Treatment Market, By Country, 2020-2030 (US$ Million) 
  7. U.S. Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  8. U.S. Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  9. Canada Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  10. Canada Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  11. Europe Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  12. Europe Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  13. Europe Hand-Foot Syndrome Treatment Market, By Country/ Region, 2020-2030 (US$ Million) 
  14. Germany Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  15. Germany Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  16. U.K. Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  17. U.K. Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  18. France Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  19. France Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  20. Italy Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  21. Italy Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  22. Spain Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  23. Spain Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  24. Rest of Europe Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  25. Rest of Europe Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  26. Asia Pacific Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  27. Asia Pacific Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  28. Asia Pacific Hand-Foot Syndrome Treatment Market, By Country/ Region, 2020-2030 (US$ Million) 
  29. China Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  30. China Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  31. Japan Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  32. Japan Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  33. India Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  34. India Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  35. South Korea Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  36. South Korea Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  37. Australia Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  38. Australia Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  39. Rest of Asia Pacific Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  40. Rest of Asia Pacific Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  41. Rest of the World Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  42. Rest of the World Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  43. Rest of the World Hand-Foot Syndrome Treatment Market, By Region, 2020-2030 (US$ Million) 
  44. Latin America Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  45. Latin America Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 
  46. Middle East and Africa Hand-Foot Syndrome Treatment Market, By Drug Class, 2020-2030 (US$ Million) 
  47. Middle East and Africa Hand-Foot Syndrome Treatment Market, By Distribution Channel, 2020–2030 (US$ Million) 

 

List of Figures

 

  1. Hand-Foot Syndrome Treatment Market Ecosystem  
  2. Snapshot of Global Hand-Foot Syndrome Treatment Market, 2020-2030 
  3. Snapshot of Global Hand-Foot Syndrome Treatment Market, By Region, 2020-2030 
  4. Global Hand-Foot Syndrome Treatment Market: COVID-19 Pandemic Impact Assessment 
  5. Global Hand-Foot Syndrome Treatment Market: Key Players & Competitive Positioning (2021) 
  6. Hand-Foot Syndrome Treatment: Market Dynamics 
  7. Global Hand-Foot Syndrome Treatment Market for Analgesics, 2020-2030 (US$ Million) 
  8. Global Hand-Foot Syndrome Treatment Market for NSAIDs, 2020-2030 (US$ Million) 
  9. Global Hand-Foot Syndrome Treatment Market for Antihistamines, 2020-2030 (US$ Million)
  10. Global Hand-Foot Syndrome Treatment Market for Multikinase Inhibitors, 2020-2030 (US$ Million) 
  11. Global Hand-Foot Syndrome Treatment Market for Others, 2020-2030 (US$ Million) 
  12. Global Hand-Foot Syndrome Treatment Market for Hospital Pharmacy, 2020-2030 (US$ Million) 
  13. Global Hand-Foot Syndrome Treatment Market for Retail Pharmacy, 2020-2030 (US$ Million) 
  14. Global Hand-Foot Syndrome Treatment Market for Online Pharmacy, 2020-2030 (US$ Million) 
  15. North America Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  16. U.S. Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  17. Canada Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  18. Europe Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  19. Germany Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  20. U.K. Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  21. France Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  22. Italy Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  23. Spain Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  24. Rest of Europe Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  25. Asia Pacific Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  26. China Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  27. Japan Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  28. India Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  29. South Korea Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  30. Australia Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  31. Rest of Asia Pacific Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  32. Rest of the World Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  33. Latin America Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  34. Middle East & Africa Hand-Foot Syndrome Treatment Market, 2020-2030 (US$ Million) 
  35. Sun Pharmaceutical Industries Revenue from 2018-2021 (US$ Million)
  36. Pfizer Inc. Revenue from 2018-2021 (US$ Million)
  37. Eli Lilly and Company Revenue from 2018-2021 (US$ Million)
  38. Merck & Co., Inc. Revenue from 2018-2021 (US$ Million)
  39. Novartis International AG Revenue from 2018-2021 (US$ Million)
  40. Teva Pharmaceutical Industries Ltd. Revenue from 2018-2021 (US$ Million)
  41. Eisai Co. Ltd. Revenue from 2018-2021 (US$ Million)
  42. GlaxoSmithKline plc Revenue from 2018-2021 (US$ Million)
  43. Celgene Corporation Revenue from 2018-2021 (US$ Million)
  44. Valeant Canada, Revenue from 2018-2021 (US$ Million)
  45. Oceanside Pharmaceuticals Revenue from 2018-2021 (US$ Million)
  46. Baxter International, Inc. Revenue from 2018-2021 (US$ Million)
  47. Biogen, Inc. Revenue from 2018-2021 (US$ Million)

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