Global Genome Editing Market
Number of pages: 100 | Report Format: PDF | Published date: March 01, 2023
Historical Years – 2020 | Base Year – 2021 | Forecasted Years – 2022-2030
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Report Attribute |
Details |
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Market Size Value in 2021 |
US$ 4.80 billion |
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Revenue Forecast in 2030 |
US$ 25.32 billion |
|
CAGR |
20.3% |
|
Base Year for Estimation |
2021 |
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Forecast Period |
2022-2030 |
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Historical Year |
2020 |
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Segments Covered |
Technology, Application, Delivery Method, Mode, End User, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global genome editing market was valued at US$ 4.80 billion in 2021 and is expected to register a revenue CAGR of 20.3% to reach US$ 25.32 billion by 2030.
Genome Editing Market Fundamentals
Genome editing, also known as gene editing, is the field of study that aims at altering the genes of living organisms to better understand the gene functioning and develop procedures to use it in diagnosing genetic or acquired diseases. This includes the addition, deletion, or modification of specific genes or nucleotide sequences in a targeted manner.
Genome editing techniques, such as CRISPR-Cas9, TALENs, and zinc finger nucleases, allow for the modification of genetic material in a specific and efficient way, providing researchers with new ways to study the genetic basis of disease, develop new treatments, and modify genetic traits. Genome editing is a rapidly advancing field with numerous potential applications in fields, such as agriculture, biotechnology, and medicine. In many different types of cells and organisms, genome editing can be used to correct, introduce, or delete almost any DNA sequence. Gene editing is carried out with the help of enzymes, specifically nucleases, which have been engineered to target a particular DNA sequence and create cuts into the DNA strands, allowing the removal of existing DNA and the insertion of replacement DNA.
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Genome Editing Market Dynamics
The increase in the adoption of CRISPR genome editing technology, which is cost-efficient, faster, and more effective, is the major driver of the global genome editing market. Moreover, the rising application of genome editing in the treatment of diseases, such as genetic disorders, cancer, cystic fibrosis, heart disease, diabetes, hemophilia, and HIV, is a key factor boosting the revenue growth of the global market.
The application of genome editing is rising in cell line development, which is used across the industry for therapeutic protein expression and epigenetic control. Furthermore, the rise in R&D and the development of biotech and pharma industries is also fueling the global market expansion. The rising government and non-government organizations’ support and the increase in investments by major players are propelling the global market revenue growth. Additionally, the increase in the adoption of advanced technology in genome sequencing and the growing demand for personalized medicine are expected to expand the global market.
However, the ethical issues associated with genome editing and off-targeted effect are the major restricting factors of the global genome editing market. The high cost of the equipment used in genome editing is also cramping the global market development.
Genome Editing Market Ecosystem
The global genome editing market has been analyzed from six perspectives: technology, application, delivery method, mode, end user, and region.
Genome Editing Market by Technology
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Based on the technology, the global genome editing market is segmented into CRISPR/Cas9, TALENs, ZFN, Meganucleases, and others.
The CRISPR/Cas9 segment dominated the global genome editing market with the largest revenue share in 2021. This can be attributed to the increased usage of the technology as it is faster, cheaper, more accurate, and more efficient than other genome editing methods. Moreover, it provides targeted gene disruption and recovery in a guide RNA-specific manner, thus increasing the demand for CRISPR/Cas9. Furthermore, a rise in the number of clinical trials for the treatment of rare diseases using CRISPR/Cas9 technology is also propelling segment growth.
Genome Editing Market by Application
Based on application, the global genome editing market is segmented into genetic engineering and clinical applications.
The genetic engineering segment accounted for the largest revenue share of the global genome editing market in 2021. The genetic engineering segment is further sub-segmented into cell line engineering, animal genetic engineering, plant genetic engineering, and others. The large share of the segment is attributed to the growing application of cell line engineering. Moreover, the rise in the usage of cell and stem cell therapy is also boosting segment growth. Cell lines are used prominently in the R&Ds related to cancer, which is increasing the demand for cell lines, thus propelling segment growth.
Genome Editing Market by Delivery Method
Based on the delivery method, the global genome editing market is segmented into ex-vivo and in-vivo.
The ex-vivo delivery method gives better control over DNA as the gene is extracted from the body. Moreover, the presence of a large product pipeline, which has been developed using genome editing and ex-vivo delivery method, is propelling segment growth. This method is commonly used in the development of cell therapies and gene therapies. The most commonly used delivery methods for ex-vivo genome editing are electroporation, lipid-mediated transfection, and viral vector delivery.
In-vivo genome editing, on the other hand, refers to the editing of cells within the body of the patient. This method is commonly used in the treatment of genetic disorders and other diseases. The most commonly used delivery methods for in-vivo genome editing are viral vector delivery and lipid-mediated transfection.
The choice of delivery method for ex-vivo and in-vivo genome editing depends on several factors, including the type of genome editing tool being used, the type of cells being edited, and the intended application of the gene editing process. As the genome editing market continues to grow, there is a growing interest in developing new and improved delivery methods for both ex-vivo and in-vivo genome editing to enhance the precision and efficiency of the gene editing process.
Genome Editing Market by Mode
Based on the mode, the global genome editing market is segmented into in-house and contract.
The contract segment led the global genome editing market, with the largest market revenue share in 2021. This can be attributed to a rise in the trend of outsourcing clinical trials. Moreover, the high cost affiliated with the infrastructure, equipment, and research of genome editing is also increasing the demand for contract-based genome editing. Similarly, contract services providers have a well-trained and experienced workforce and infrastructure of clinical trials, thus boosting segment growth.
Genome Editing Market by End User
Based on the end user, the global genome editing market is segmented into biotechnology and pharmaceutical companies, academic and government research institutes, and contract research organizations.
The biotechnology and pharmaceutical companies segment accounted for a significant share of the global market in 2021. The growing R&D and development of novel drugs and therapeutics are propelling revenue growth of the segment. Moreover, the continuous product launches and the collaboration of key companies to create new drugs are also boosting growth.
Genome Editing Market by Region
Based on the region, the global genome editing market has been segmented into North America, Europe, Asia Pacific, and the Rest of the World.
North America dominated the global genome editing market in 2021, followed by Europe and Asia Pacific. The large share of the region can be attributed to the rise in the R&D and clinical trials related to genomics. Additionally, the growing investment in developing new therapeutics for rare diseases is fueling regional growth. Similarly, the presence of major market players in the region is also expected to propel regional growth.
Genome Editing Market Competitive Landscape
The prominent players operating in the global genome editing market are:
Genome Editing Market Strategic Developments
Genome editing, also known as gene editing, is a field of study that aims at altering the genes of living organisms to better understand the gene functioning and develop procedures to use it in diagnosing genetic or acquired diseases.
North America accounts for the largest market revenue share, followed by Europe; and Asia Pacific is expected to be the fastest-growing region during the forecast period.
Some of the key companies are Merck KGaA, Sangamo Therapeutics Inc., Thermo Fisher Scientific Inc., Horizon Discovery Ltd., and GenScript.
The genome editing market is expected to grow at a revenue CAGR of 20.3% during the forecast period.
The CRISPR/Cas9 segment dominates the global genome editing market.
*Insights on financial performance are subject to the availability of information in the public domain