Number of pages: 100 | Report Format: PDF | Published date: March 13, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
Report Attribute |
Details |
Market Size Value in 2022 |
US$ 580 million |
Revenue Forecast in 2031 |
US$ 1,235 million |
CAGR |
8.76% |
Base Year for Estimation |
2022 |
Forecast Period |
2023-2031 |
Historical Year |
2021 |
Segments Covered |
Treatment Type, Drug Class, End-user, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global glioblastoma treatment market was valued at US$ 580 million in 2022 and is expected to register a revenue CAGR of 8.76% to reach US$ 1,235 million by 2031.
Glioblastoma Treatment Market Fundamentals
Glioblastoma is a type of malignant brain tumor that arises from astrocytes, which are star-shaped cells that support nerve cells in the brain. It is the most aggressive type of primary brain tumor, meaning it originates in the brain rather than spreading from another part of the body. It can quickly invade nearby tissues. The exact cause of glioblastoma is unknown, but it is believed to occur due to genetic mutations that result in uncontrolled growth and division of cells in the brain. Glioblastoma is more common in adults than children, affecting men more often than women. Symptoms of glioblastoma may include headaches, seizures, changes in mood or behavior, and problems with vision or speech.
Treatment for glioblastoma typically involves surgery to remove as much of the tumor as possible, followed by radiation therapy and chemotherapy. However, as glioblastoma cells can quickly multiply and spread, the prognosis for this type of tumor is often poor, with most patients surviving only 15 months to 2 years after diagnosis. Despite aggressive treatment, glioblastoma often recurs. Researchers are working to develop new treatments for glioblastoma, such as immunotherapy, which uses the body’s immune system to attack cancer cells. Clinical trials are also exploring targeted therapies that aim to block specific genetic mutations that drive the growth of glioblastoma cells.
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Glioblastoma Treatment Market Dynamics
The rising incidence of glioblastoma globally is the major growth driver of the global glioblastoma treatment market. For instance, according to the Brain Tumor Society, glioblastoma is one of the most complex, fatal, and resistant to the treatment of malignancies. In 2022, more than 13,000 people were expected to be diagnosed with glioblastoma. There is a growing pipeline of treatments for glioblastoma, including targeted therapies and immunotherapies. The new treatments have the potential to improve survival rates and quality of life for patients, which will fuel the revenue growth of the global glioblastoma treatment market. Additionally, advances in technology, such as precision medicine and genetic testing, are enabling researchers to understand the biology of glioblastoma better and develop more targeted treatments, which eventually results in the revenue growth of the global glioblastoma treatment market. Moreover, governments and healthcare organizations are investing more in the research and development of new treatments and improving patient care access, which will propel the global glioblastoma treatment market.
However, the cost of treating glioblastoma can be very high, particularly for newer immunotherapies and targeted therapies. This can be a barrier for patients who cannot afford these treatments and limit the market potential for these therapies. Moreover, despite advances in research, much is still not understood about the biology of glioblastoma. This can hinder the development of new treatments that effectively target the disease and hamper market revenue growth. Additionally, limited treatment options, regulatory challenges, and poor reimbursement policies in emerging nations are some restraints of the market revenue growth.
Glioblastoma Treatment Market Ecosystem
The global glioblastoma treatment market is analyzed from four perspectives: treatment type, drug class, end-user, and region.
Glioblastoma Treatment Market by Treatment Type
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Based on the treatment type, the global glioblastoma treatment market is segmented into surgery, radiation therapy, chemotherapy, targeted therapy, tumor treating field (TTF) therapy, and immunotherapy.
The radiation therapy segment dominated the market with the principal revenue share in 2022, attributed to improved survival rates. Radiation therapy offers high-energy radiation to kill cancer cells or slow their growth. It is a non-invasive treatment that does not require surgery or incisions. In glioblastoma treatment, radiation therapy can be delivered externally, using a linear accelerator to target the tumor from outside the body, or internally by placing radioactive material directly into the tumor bed. Radiation therapy can also shrink the size of the tumor, reducing pressure on the brain and relieving symptoms, such as headaches and seizures. This can make it a more attractive option for patients who may not be candidates for surgery. Radiation therapy is often combined with surgery and chemotherapy, allowing for a multi-modal approach to treating glioblastoma, thus resulting in better patient outcomes. Advances in radiation therapy techniques, such as intensity-modulated radiation therapy and proton therapy, have improved outcomes for patients with glioblastoma. These factors contribute to the revenue growth of the radiation therapy segment.
The targeted therapy segment is expected to be the fastest-growing segment throughout the forecast period, owing to the development of new drugs targeting these pathways. Targeted therapy is a treatment approach involving drugs that specifically target cancer cells while minimizing damage to healthy cells. Targeted therapy drugs for glioblastoma work by targeting specific molecular pathways involved in cancer cells’ growth and survival. These drugs can block the activity of proteins that promote cancer growth or stimulate the immune system to attack cancer cells. One example of a targeted therapy drug for glioblastoma is bevacizumab, which targets the protein VEGF (vascular endothelial growth factor) that stimulates the growth of new blood vessels in tumors. By blocking VEGF, bevacizumab can slow the growth of tumors and improve survival in some patients with glioblastoma. These factors contribute to the revenue growth of the targeted therapy segment.
Glioblastoma Treatment Market by Drug Class
Based on the drug class, the global glioblastoma treatment market is segmented into nitrosoureas, anticonvulsants, steroids, and other drugs. The other drugs segment includes drugs, such as bevacizumab and temozolomide.
Bevacizumab is a targeted therapy drug that blocks the growth of blood vessels that supply the tumor. It has been approved by the U.S. Food and Drug Administration (FDA) for treating recurrent glioblastoma (rGBM) in adults. Bevacizumab is typically used with chemotherapy, such as temozolomide, to improve outcomes in patients with rGBM. The usage of bevacizumab in glioblastoma treatment has been controversial due to conflicting evidence on its efficacy and safety. While some studies have shown that it can improve progression-free survival and quality of life for patients with rGBM, others have not significantly improved survival rates. Temozolomide is an oral chemotherapy drug that is widely used in the treatment of glioblastoma. It is a prodrug converted into an active compound in the body, which then damages the DNA of cancer cells, preventing them from dividing and multiplying. Temozolomide is also used with radiation therapy as a first-line treatment for newly diagnosed glioblastoma. It has been shown to improve survival rates and delay disease progression in patients with this type of brain cancer, contributing to the growth of the other drugs segment.
Glioblastoma Treatment Market by End-user
Based on the end-user, the global glioblastoma treatment market is segmented into hospitals, ambulatory surgical centers, and others.
The hospitals segment dominated the global glioblastoma treatment market with the largest revenue share in 2022, as they are the primary setting for diagnosing and treating this disease. Hospitals have established multidisciplinary teams of neuro-oncology specialists, including neurosurgeons, radiation oncologists, medical oncologists, and neurologists. Hospitals provide various services for patients with glioblastoma, including surgery, radiation therapy, chemotherapy, and supportive care. In addition to providing treatment, hospitals also play a critical role in clinical trials of new therapies for glioblastoma. Clinical trials are essential for advancing the field of glioblastoma treatment and improving outcomes for patients. Hospitals also provide supportive care services for patients with glioblastoma, including pain management, nutrition counseling, and psychological support. Supportive care is an important aspect of glioblastoma treatment, as it can improve quality of life and help patients and their families cope with the challenges of this disease. These overall factors contribute to the growth of the hospital segment.
Glioblastoma Treatment Market by Region
Geographically, the global glioblastoma treatment market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America dominated the global glioblastoma treatment market with the largest revenue share in 2022, attributed to high awareness of rare disorders, easy access to high-quality medical care, and attractive reimbursement policies. Additionally, companies across the region are continuously involved in the research and development of novel drugs as well as treatments, which is also helping in the market revenue growth. For instance, in March 2023, SonALAsense, a pioneer in developing non-invasive Sonodynamic Treatment (SDT), employs SONALA-001 in conjunction with Insightec’s MR-guided focused ultrasound (MRgFUS), announced the completion of the first cohort in SDT-202. SDT-202 is an open-label, dose-escalation study of SDT in patients with rGBM. SDT-202, which expands on a prior proof-of-concept experiment at Barrow Neurological Institute, aims to assess the safety, appropriate dosage, and effectiveness of SDT.
Glioblastoma Treatment Market Competitive Landscape
The prominent players operating in the global glioblastoma treatment market are:
Glioblastoma Treatment Market Strategic Developments
Glioblastoma is a type of malignant brain tumor that arises from astrocytes, which are star-shaped cells that support nerve cells in the brain.
The global glioblastoma treatment market is expected to reach US$ 1,235 million by 2031.
The revenue CAGR of the glioblastoma treatment market will be 8.76% during the forecast period from 2023 to 2031.
The limited treatment options, regulatory challenges, and poor reimbursement policies in emerging nations restrict global market revenue growth to its full potential.
Some prominent players operating in the global glioblastoma treatment market are Accuray Inc., Brainlab AG, Bristol-Myers Squibb, Northwest Biotherapeutics, and AstraZeneca.
*Insights on financial performance are subject to the availability of information in the public domain
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