Number of pages: 100 | Report Format: PDF | Published date: February 02, 2023
Historical Years – 2020 | Base Year – 2021 | Forecasted Years – 2022-2030
Report Attribute |
Details |
Market Size Value in 2021 |
US$ 282 million |
Revenue Forecast in 2030 |
US$ 452.7 million |
CAGR |
5.4% |
Base Year for Estimation |
2021 |
Forecast Period |
2022-2030 |
Historical Year |
2020 |
Segments Covered |
Product, Modality, Patient Type, Application, and Region |
Regional Scope |
North America, Europe, Asia Pacific, and the Rest of the World (RoW) |
According to the deep-dive market assessment study by Growth Plus Reports, the global extracorporeal membrane oxygenation (ECMO) machine market was valued at US$ 282 million in 2021 and is expected to register a revenue CAGR of 5.4% to reach US$ 452.7 million by 2030.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market Fundamentals
Extracorporeal membrane oxygenation (ECMO), commonly referred to as extracorporeal life support (ECLS), is a therapy for prolonging cardiac and respiratory support for people whose hearts and lungs cannot generate sufficient gas exchange or perfusion to preserve life. This technique allows blood to bypass the heart and lungs, providing these organs time to rest and recuperate. ECMO could be useful in treating COVID-19, ARDS, and other prevalent infections. The primary purpose of ECMO is to exchange gas, both oxygen and CO2. Blood film thickness, membrane material, the fraction of inspired oxygen (FIO2), and hemoglobin content affect oxygen exchange across the membrane oxygenator.
ECMO has made significant advances in recent years; it is a crucial part of treating adults and children with severe cardiac and pulmonary dysfunction and patients resistant to traditional treatments. The most prevalent cardiac indication for ECMO is the inability to safely wean from the CPB circuit after heart surgery. Other cardiac indications include myocarditis, decompensated cardiomyopathy, acute coronary syndrome, cardiogenic shock, and primary graft failure following heart transplantation. Due to the possibility of heart transplantation, patients with irreversible cardiac disease frequently use ECMO. Adult respiratory distress syndrome, acute respiratory distress syndrome, primary graft failure following lung transplantation, and trauma also indicate the usage of ECMO in respiratory failure.
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Extracorporeal Membrane Oxygenation (ECMO) Machine Market Dynamics
Over the years, the demand for ECMO in lung transplantation procedures has significantly increased. Lung transplantation is a challenging process that frequently requires extracorporeal mechanical cardiopulmonary support. Depending on the severity of the patient's disease and clinical status, ECMO assistance is offered before, during, or after surgery. Most common situations which require assistance during the perioperative phase include pulmonary arterial hypertension (PAH), right ventricular failure, and intolerance to single lung breathing.
Technological advancements in the field of ECMO also influence market revenue growth. The technical components are always evolving and have gone from a collection of separate parts to more integrated systems with extra features, increased safety, and improved flexibility. Polymethylpentene (PMP) fiber technology has advanced the creation of artificial membranes with low resistance, greater biocompatibility, and longer usage intervals. For instance, TandemLung Oxygenator, developed by LIVANOVA PLC for patients who need cardiac or respiratory support, transfers oxygen into the blood using cutting-edge polymethylpentene (PMP) fibers.
However, the high cost of ECMO procedures can restrict the revenue growth of the market to some extent.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market Ecosystem
The global extracorporeal membrane oxygenation (ECMO) machine market has been analyzed from five perspectives: product, modality, patient type, application, and region.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market by Product
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Based on the product, the global extracorporeal membrane oxygenation (ECMO) machine market is segmented into ECMO machines and software.
The ECMO machine segment is sub-segmented into static and portable ECMO machines. The ECMO machine accounted for the majority of the market revenue share in 2021. Portable ECMO devices help critical care teams to efficiently treat patients with cardiac arrest and respiratory failure. Additionally, these systems can provide life support in a critical 60-minute period after a heart attack. Technological advancements in this segment are also likely to boost revenue growth in the upcoming years. In patients with acute respiratory failure, a small, portable Cardiohelp ECMO device by Getinge is incredibly effective in ensuring critical gas exchange and reducing future ventilator-induced lung injury. Important technical advancements make it simple to transport and implant devices, enabling location-independent stabilization with the subsequent inter-hospital transfer.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market by Modality
Based on the modality, the global extracorporeal membrane oxygenation (ECMO) machine market is segmented into venoarterial ECMO, Venovenous ECMO, and Arteriovenous (AV) ECMO.
The arteriovenous ECMO segment dominates the extracorporeal membrane oxygenation (ECMO) machines market. AV-ECMO enables gas exchange by pumping blood from the artery to the venous side using the patient's arterial pressure. Moreover, arteriovenous ECMO is especially beneficial in newborns with hypoxia and high pulmonary vascular resistance. The venoarterial ECMO segment is expected to grow at a high revenue CAGR during the forecast period owing to its efficiency and reliability in the exchange of gases, extensive application in cardiac arrest, and capability of algorithmic life support procedures to restore blood flow. In cases of rapid decompensation, it is frequently used to treat patients with thromboembolism and pulmonary hypertension, fueling the revenue growth of the extracorporeal membrane oxygenation (ECMO) machine market.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market by Patient Type
Based on the patient type, the global extracorporeal membrane oxygenation (ECMO) machine market is segmented into neonates, pediatric patients, and adults.
The adult segment accounted for the majority of the revenue share of the market in 2021. The high population affected with respiratory disorders is the major factor influencing segment revenue growth. According to the CDC (Centers for Disease Control and Prevention), about 4.6% of the adult population in the U.S. was diagnosed with COPD, emphysema, or chronic bronchitis in 2021.
The pediatric segment is expected to grow at a high revenue CAGR during the forecast period. The growing number of children suffering from different pulmonary and cardiac diseases influences the segment revenue growth. Congenital diaphragmatic hernia is the most common disorder treated with ECMO. According to an NCBI report published in 2021, a congenital diaphragmatic hernia (CDH) is a serious birth abnormality defined by a diaphragmatic distortion that allows lower abdominal organs to protrude into the thoracic cavity. CDH affects one in every 3,000 alive babies globally. ECMO is used to treat this condition when standard care fails.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market by Application
Based on the application, the global extracorporeal membrane oxygenation (ECMO) machine market is segmented into respiratory, cardiac, and EPCR.
The respiratory segment accounted for the highest revenue share in 2021. The segment is predicted to rise rapidly during the forecast period. The primary factors for the large market share of this category are the high prevalence of respiratory diseases, increased smoking and tobacco usage, excessive alcohol usage, and the resulting high incidence of chronic diseases or respiratory failures. In addition, neonates are one of the main patient groups driving demand for respiratory ECMO devices as ECMO machines are frequently used to treat a wide range of diseases, such as pneumonia, respiratory distress syndrome, and congenital diaphragmatic hernia (CDH).
Extracorporeal Membrane Oxygenation (ECMO) Machine Market by Region
Regionally, the global extracorporeal membrane oxygenation (ECMO) machine market has been segmented into North America, Europe, Asia Pacific, and the rest of the world.
The market in North America is anticipated to register revenue growth at a significant pace during the forecast period. This can be ascribed to the large patient pool of chronic obstructive pulmonary disease (COPD) in the United States and Canada. Advanced healthcare facilities and favorable reimbursement policies support the high uptake of ECMO machines in North America.
The market in Europe accounted for a big proportion of the market’s revenue share in 2021. This is attributed to the increased adoption of advanced ECMO devices by healthcare facilities in European countries and the region’s growing patient population suffering from respiratory and cardiac problems. Germany contributes a larger revenue share to the Europe extracorporeal membrane oxygenation (ECMO) machine market due to the rapid adoption of advanced technologies and significant R&D spending in the healthcare industry.
The Asia Pacific extracorporeal membrane oxygenation (ECMO) machine market is expected to grow at the highest revenue CAGR during the forecast period due to rising healthcare standards in the region. Developing countries, such as China, are expected to observe significant revenue growth opportunities owing to the consistent patient pool increase and healthcare expenditure. Additionally, increased grants by the regional governments are also influencing the market in Asia Pacific. For instance, the National Health Commission (NHC) approved China’s first ECMO device for sale in January 2023. The National Medical Products Administration (NMPA), a division of the NHC, announced that the permit was provided to fulfill the need for treatment in severe COVID-19 cases.
Extracorporeal Membrane Oxygenation (ECMO) Machine Market Competitive Landscape
The prominent players operating in the global extracorporeal membrane oxygenation (ECMO) machine market are:
The global extracorporeal membrane oxygenation (ECMO) machine market is influenced by the increased incidence of cardiopulmonary disorders, respiratory failures, and the increased number of patients needing respiratory therapies. Additionally, the market is driven by government activities to raise awareness about certain disorders and benefits of ECMO devices, technological developments in the healthcare sector, and significant R&D expenditure on innovations.
Microport Scientific Corporation, Xenious AG, Medtronic Plc, Terumo Group, Getinge AB, and EUROSETS S.R.L are among the prominent market players.
The high cost of ECMO procedures is restraining the uptake of ECMO machines in remote regions.
The global extracorporeal membrane oxygenation (ECMO) machine market is expected to register a revenue CAGR of 5.4% during the forecast period from 2022 to 2030.
The respiratory application segment accounts for the largest revenue share of the global extracorporeal membrane oxygenation (ECMO) machine market.
*Insights on financial performance are subject to the availability of information in the public domain