Cytogenetics Market
Number of pages: 100 | Report Format: PDF | Published date: March 10, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
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Report Attribute |
Details |
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Market Size Value in 2022 |
US$ 3.38 billion |
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Revenue Forecast in 2031 |
US$ 7.40 billion |
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CAGR |
9.10% |
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Base Year for Estimation |
2022 |
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Forecast Period |
2023-2031 |
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Historical Year |
2021 |
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Segments Covered |
Products, Application, Techniques, End-user and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global cytogenetics market was valued at US$ 3.38 billion in 2022 and is expected to register a revenue CAGR of 9.10% to reach US$ 7.40 billion by 2031.
Cytogenetics Market Fundamentals
Cytogenetics studies chromosome changes in tissue, blood, or bone marrow samples in a laboratory to look for broken, missing, altered, or additional chromosomes. Modifications in specific chromosomes may indicate a hereditary disease, condition, or certain types of cancer. Chromosomes are structures of DNA strands and proteins that contain most of a cell’s genetic information. During the cell cycle, we may see chromosomes in metaphase. In a laboratory, tissue, blood, blood marrow, or culture cells are analyzed through bands or manipulation procedures to detect chromosome abnormalities, such as damaged, missing, rearranged, or additional chromosomes. Chromosome changes may indicate a hereditary disease or condition. Cytogenetics can aid in the diagnosis, therapy planning, and determining how well a treatment works.
Several cytogenetics banding techniques and molecular cytogenetics, such as fluorescent in situ hybridization (FISH) and comparative genomic hybridization, are utilized in the karyotyping study of G-banded chromosomes (CGH). This specimen requirement is very restrictive as, at certain hospitals, specimens are received in the cutting room already fixed in formalin, or the pathologist may place it in formalin prematurely. To employ the karyotyping procedure, the pathologist must prepare and submit a viable piece of the specimen before fixation. Furthermore, the applications of molecular cytogenetics in pharmacogenomic research are expected to substantially impact market revenue growth, as various cytogenetic tools have been successfully employed in pharmacogenomic biomarker investigations. Many published studies illustrating the role of cytogenetic techniques in pharmacogenomic testing demonstrate the effective use of CGH, FISH, and sequencing technology in pharmacogenomic testing.
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Cytogenetics Market Dynamics
The rising prevalence of cancer and genetic abnormalities directly impacts the cytogenetics market. According to the American Cancer Society, 1.9 million people were expected to be diagnosed with cancer in the United States in 2022. Cancer cytogenetics not only provides crucial information to help with cancer treatment, but it also guides the identification of the genes that produce neoplastic states, fueling the development of molecularly targeted medicines in personalized medicine. As a result, the rise in cancer incidences is expected to boost market revenue growth over the forecast period. Furthermore, the genetic data collected daily is intimately related to neoplasm diagnosis and prognosis, broadening the scope of cancer cytogenetics in diverse disciplines. Molecular cytogenetics has many applications in genetic illnesses, such as Down, Edwards, Patau, and Turner syndrome. For instance, according to a research article published in March 2022 in the journal Molecular Cytogenetics, a patient with Turner syndrome exhibited diverse symptoms and was found to have a rare mosaic X-ring chromosome through a cytogenetic microarray experiment. The researchers determined the phenotype of the patient with a rare genotype and Turner syndrome based on clinical symptoms, ultrasonography diagnostic, and cytogenetics. Similarly, in an article published in PubMed in July 2022, the researchers emphasized the importance of cytogenetic studies supplemented with molecular cytogenetic studies and karyotype-phenotype correlations in Turner Syndrome patients to obtain information about genotype-phenotype correlations related to the X chromosome. The need for molecular cytogenetics is predicted to expand significantly in the forecast years due to their increased usage in identifying phenotypes in various genetic illnesses.
The increased usage of genetic information in predictive models for disease features directly impacts the use of cytogenetic procedures, which in turn enhances money generation. The various research facilities in China, India, and Japan, as well as R&D facilities, will increase demand for top-tier molecular cytogenetics. As a result of long-standing collaborations between industry and academic institutions, Japan leads the globe in contributions to the cytogenetics market. Furthermore, developed countries are beginning to understand the importance of personalized medicine in treating genetic or other ailments, which is expected to drive the market throughout the projection period.
However, technological limits and equipment complexity are expected to limit the expansion of the molecular market over the projected period.
Cytogenetics Market Ecosystem
The global cytogenetics market is analyzed from five perspectives: products, applications, techniques, end-user, and region.
Cytogenetics Market by Products
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Based on products, the global cytogenetics market has been segmented into instruments, consumables, software & services.
Advances in molecular biology techniques have also accelerated the development of accompanying consumables, reagents, kits, and software. The consumables segment accounts for the largest revenue share of the market due to the increased usage of media and reagents during cytogenetic analysis. Consumables contribute to achieving accurate and consistent results in regular and advanced clinical cytogenetic techniques. Nevertheless, due to the constant development of solutions and algorithms to manage and interpret enormous volumes of genetic data, the software and services segment is projected to be a valuable revenue source in the future.
Cytogenetics Market by Application
Based on application, the global cytogenetics market has been segmented into genetic disorders, oncology, personalized medicine, and others.
The personalized medicine segment is expected to show lucrative revenue growth during the forecast period. Pharmacotherapies and personalized treatment options are the two most essential tools for improving treatment outcomes. With a shift towards customized therapy, molecular cytogenetic techniques are likely to increase profitably over the forecast period. This is mostly due to the vast range of applications of molecular cytogenetic analysis in cytoproteomics, cytogenomics, drug discovery and development, and biomarker discovery.
Cytogenetics Market by Techniques
Based on techniques, the global cytogenetics market has been segmented into comparative genomic hybridization (CGH), fluorescence in situ hybridization (FISH), karyotyping, immunohistochemistry, and others.
The CGH & FISH segments are expected to dominate the market during the forecast period. The numerous advantages of CGH and FISH techniques over conventional procedures have allowed these segments to account for a significant part of the market. CGH dominated the market due to its vital position in comprehensive cancer research. The great resolution provided by array-based CGH has also aided its growth. In terms of labor requirements and resolution, array-based CGH has greatly overcome the constraints of regular CGH. This method also eliminates the need for metaphase chromosomes, resulting in improved resolution.
Cytogenetics Market by End-user
Based on end-user, the global cytogenetics market has been segmented into clinical & research laboratories, hospitals & pathology laboratories, academic research institutes, pharmaceutical and biotechnology companies, and others.
The clinical & research laboratories segment is expected to dominate the market during the forecast period. This is mostly due to the increasing usage of cytogenetic techniques in clinical diagnosis. This segment accounts for the largest revenue share due to ongoing studies into the processes underlying various chromosomal illnesses.
Given the increasing demand for targeted medicines, the usage of molecular cytogenetics in pharmaceutical and biotech firms is likely to increase rapidly. Throughout the projection period, the prevalent trend of companion diagnostics is projected to support the expansion of this segment.
Cytogenetics Market by Region
Based on region, the global cytogenetics market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
The North America cytogenetics market is expected to grow significantly due to improved healthcare infrastructure, effective government regulations, a large base of multinational corporations, and an increase in genetic illnesses in the region. According to the Diagnostic and Statistical Manual of Mental Disorders, the Indiana Health Coverage Program module published in May 2022 covers chromosomal microarray analysis, when it is determined to be medically necessary for diagnosing a genetic abnormality in children with apparent nonsyndromic cognitive developmental delay/intellectual delay or autism spectrum disorder. According to the Canadian Cancer Society, the expected number of cancer diagnoses in Canada in 2022 was about 233,900. The most common cancers are breast, prostate, and colorectal cancers. They account for over half of all prevalent instances when combined. As a result of the increasing prevalence of cancer instances in North America, cytogenetics applications are predicted to drive the studied market throughout the forecast period.
Pfizer was awarded a medical grant in May 2022 to support the global healthcare community’s autonomous activities (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need aligned with Pfizer’s medical and scientific strategy. The money was provided for the study Improving Cytogenetic Testing & Therapy Guidance in Adult AML, which focused on the geographic scope of Canada.
The Asia Pacific cytogenetics market is expected to grow significantly during the forecast period. Companies in Asia Pacific are focusing on broadening their product portfolios, diversifying their business operations, lowering costs, increasing user satisfaction, and improving Cytogenetics reliability. Effective customer-focused strategies are required in the face of rising consumer expectations.
Cytogenetics Market Competitive Landscape
The cytogenetics market is fairly fragmented, with large and small market participants competing for a limited share of the global landscape. Companies in the market place a premium on aggressive marketing methods to reach a big consumer base. New research initiatives, partnerships, distribution network development, R&D spending, and mergers and acquisitions are key tactics firms utilize to strengthen their reach and expand their market share.
The key players in the global cytogenetics market include:
Cytogenetics Market Strategic Developments
Cytogenetics studies chromosome changes in tissue, blood, or bone marrow samples in a laboratory to look for broken, missing, altered, or additional chromosomes.
The cytogenetics market is expected to be valued at US$ 7.40 billion by 2031.
The cytogenetics market is expected to register a revenue CAGR of 9.1% during the forecast period.
Some of the key players in the global cytogenetics market include Abbott Laboratories, Agilent Technologies, Inc., and Applied Spectral Imaging, Inc.
The consumables product segment leads the global cytogenetics market.
*Insights on financial performance are subject to the availability of information in the public domain