Number of pages: 100 | Report Format: PDF | Published date: March 24, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
Report Attribute |
Details |
Market Size Value in 2022 |
US$ 3.6 billion |
Revenue Forecast in 2031 |
US$ 11.3 billion |
CAGR |
12.2% |
Base Year for Estimation |
2022 |
Forecast Period |
2023-2031 |
Historical Year |
2021 |
Segments Covered |
Product, Application, End User, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global cell & tissue preservation market was valued at US$ 3.6 billion in 2022 and is expected to register a revenue CAGR of 12.2% to reach US$ 11.3 billion by 2031.
Cell & Tissue Preservation Market Fundamentals
A crucial component of cell and tissue culture is the maintenance of cells and tissues. Animal cells can only be preserved effectively through freezing, which can be done using either liquid nitrogen or cryogenic freezers. To freeze cells, their temperature must first be gradually dropped to between -30°C and -60°C and then transferred to an environment below -130°C. Throughout cryopreservation, a chemical substance, that is a cryoprotective agent, is employed to shield the cellular structures from damage throughout the freezing and rewarming processes. Since cryopreservation enables the long-term storage of cells and tissues, it has emerged as a crucial technique in contemporary medicine and biotechnology. This technique has been effectively applied in several sectors, including cancer treatment, stem cell research, and organ transplantation. The best method for biopreservation depends on the type and complexity of the tissue and the amount of time that must be stored. Over time, techniques for preserving cells and tissues have developed significantly. All methods of biopreservation, more recently, normothermic organ perfusion, aim to stabilize biological tissues by obstructing metabolism and consider delaying the chemical and biochemical processes that cause degradation during ex vivo storage. Innovative and prompted by freeze tolerance or freeze avoidance mechanisms seen in nature, these paradigms for high-subzero preservation are fresh and understudied. Others use novel bioengineering methods, such as nanotechnology, isochoric pressure preservation, and non-Newtonian fluids, to solve unsolvable cryopreservation issues.
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Cell & Tissue Preservation Market Dynamics
The increasing preservation of stem cells is a major driver for the revenue growth of the global cell & tissue preservation market. The global market for cell & tissue cryopreservation is anticipated to rise as scientists and physicians conduct advanced stem cell research and development. For instance, the California Institute for Regenerative Medicine awarded a US$ 5 million grant to the University of Southern California in November 2021 to support the advancement of Ph.D. candidates, clinical research fellows, and postdoctoral researchers in stem cell research. During the projection period, it is anticipated that increasing expenditures in smart technology adoption, healthcare infrastructure development, and medical innovation would support market revenue growth. The prevalence of numerous chronic diseases, including cardiovascular conditions, a wide range of cancers, diabetes, neurological disorders, and many other illnesses, is rising worldwide, considerably encouraging the revenue growth of the worldwide cell & tissue preservation market. Due to increased research funding, the availability of sophisticated healthcare infrastructure, and increased healthcare spending, better access to better healthcare facilities has sparked the development of cutting-edge bio-preservation technologies and facilities.
Governments worldwide are continually making investments to grow the biopharmaceutical sector. The main market participants are working with governmental organizations to launch new cell therapies on the international market. Additionally, industry participants focus on established and developing nations to expand the global cell preservation market. The increasing prevalence of numerous chronic conditions, growing healthcare costs, and the upcoming patent expirations of several well-known medications worldwide significantly contribute to the growth of worldwide drug discovery activities. The prevalence of diseases, such as cancer, diabetes, respiratory illnesses, cardiovascular diseases, and neurological disorders, is increasing worldwide, dramatically boosting the demand for novel and cutting-edge medications. The pharmaceutical business, which is expanding tremendously due to the quick development of biopharmaceuticals, is anticipated to grow significantly in the years to come. Cell line generation is crucial in determining the effectiveness of drug discovery, toxicity, and in vitro testing. It requires less time, effort, and money, which minimizes the likelihood that research drugs will fail during the clinical trial stage. For that purpose, cell preservation is the most important factor.
However, the availability of alternative options for cell cryopreservation and the high maintenance costs associated with the storage technique impede market expansion. According to the National Institute of Health data published in 2019, a newly developing technology known as cryoprotective agent-free cryopreservation of mammalian cells or super flash freezing works by a heat-transfer stimulation sufficient to nearly vitrify the cells. Conversely, the cell cryopreservation market opportunity includes manufacturers’ increased focus on developing unique solutions for preserving diverse cells.
Cell & Tissue Preservation Market Ecosystem
The global cell & tissue preservation market is analyzed from four perspectives: product, application, end user, and region.
Cell & Tissue Preservation Market by Product
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Based on the product, the global cell & tissue preservation market is segmented into equipment, bio-preservation media, and others.
The equipment segment accounted for the largest revenue share of the global cell & tissue preservation market in 2022. Cryogenic products are stored using cryopreservation equipment. Cryopreservation freezers are most commonly used to preserve embryos and oocytes during an in-vitro fertilization cycle before treatment for women with breast cancer to retain their reproductive capacity. Rising investment in research and development in life sciences, such as vaccines, is expected to boost segment revenue growth. The rising adoption of freezing and storage technologies to preserve cells and tissues has resulted in this higher revenue share in the global market. Furthermore, the increased expenditures of acquiring new and innovative equipment contributed to larger revenue generation.
Cell & Tissue Preservation Market by Application
Based on the application, the global cell & tissue preservation market is segmented into therapeutics, research and development, drug discovery, and others.
The Therapeutics segment accounted for the largest revenue share of the global cell & tissue preservation market in 2022. The increasing requirement for cell and tissue preservation to develop therapies to cure different chronic and noncommunicable illnesses has resulted in the segment revenue growth worldwide. Over the forecast period, the rapidly increasing prevalence of lifestyle and age-related disorders will likely fuel this segment’s revenue growth. Cell culture is a powerful cellular and molecular biology technique because it provides appropriate model systems for studying normal cell physiology and biochemistry, the effects of medicines and harmful substances on cells, and mutagenesis and carcinogenesis. It is also used for drug testing, research, and large-scale biological chemical production. Because of the homogeneity and reproducibility of results obtained by clonal cells, cell culture is highly valuable for all this research and new therapeutics development. Therefore, cell preservation is the most crucial process to be performed for the development of new therapeutics.
Cell & Tissue Preservation Market by End User
Based on the end user, the global cell & tissue preservation market is segmented into biobanks, hospitals, academic and research centers, and others.
The biobanks segment accounted for the largest revenue share of the global cell & tissue preservation market in 2022. The growing popularity of precision/personalized medicine and genetic testing has been a major market driver. Biobanks have played a key role in biomedical research. Platforms and technologies used in genetic studies have advanced significantly during the last few decades. This has increased the need for clinical lab biospecimens to create assays for genetic testing. Collaborations between corporate and public entities in biobanking have been critical to segment revenue growth. Through the development of novel methods and concepts of synergy pioneered by public and commercial entities, digitalization, precision medicine, and virtualization are fast altering the biobanking business. Cryopreservation procedures and cryopreserved products are used in cutting-edge research in areas such as discovery science, stem cell research, diagnostic development, and customized medicine. The rise in cryopreserved cell usage is propelling the demands in the biobanking business, which is rapidly growing and expanding.
Cell & Tissue Preservation Market by Region
On the basis of region, the global cell & tissue preservation market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America accounted for the largest revenue share of the global cell & tissue preservation market in 2022. The presence of improved healthcare infrastructure and an increase in government spending on healthcare technology research and development have considerably fueled the revenue growth of the cell and tissue preservation industry. The rising prevalence of chronic diseases among the U.S. population has attracted significant investment in drug research and the development of novel treatments, fueling the expansion of the North America cell & tissue preservation market.
During the forecast period, Asia Pacific is expected to be the most opportunistic market. The increasing investments in the development of modern healthcare and medical infrastructure and the presence of several top pharmaceutical businesses and research institutions are all helping to drive the Asia Pacific cell & tissue preservation market forward.
Cell & Tissue Preservation Market Competitive Landscape
Notable market participants include:
Cell & Tissue Preservation Market Strategic Developments
Cell & tissue preservation, known as cryopreservation, is preserving organelles, cells, tissues, or other biological constructions by freezing them at extremely low temperatures.
Increased research and development and drug discovery are the major factors that propel the revenue growth of the global cells & tissue preservation market.
The high cost of the reagents and instruments restricts the revenue growth of the global cells & tissue preservation market.
Key companies operating the global cell & tissue preservation market are Thermo Fisher Scientific, Inc., Lonza, BD, Merck KGaA, Cytiva, and Agilent Technologies, Inc.
The global cell & tissue preservation market is expected to grow at a revenue CAGR of 12.2% during the forecast period from 2023 to 2031.
*Insights on financial performance are subject to the availability of information in the public domain