Cell Dissociation Market
Number of pages: 100 | Report Format: PDF | Published date: June 09, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023 to 2031
|
Report Attribute |
Details |
|
Market Size Value in 2022 |
US$ 310.5 million |
|
Revenue Forecast in 2031 |
US$ 875.0 million |
|
CAGR |
12.2% |
|
Base Year for Estimation |
2022 |
|
Forecast Period |
2023 to 2031 |
|
Historical Year |
2021 |
|
Segments Covered |
Products, Type, End User, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global cell dissociation market was valued at US$ 310.5 million in 2022 and is expected to register a revenue CAGR of 12.2% to reach US$ 875.0 million by 2031.
Cell Dissociation Market Fundamentals
Cell dissociation is the process of isolating individual cells or small cell clusters by removing them from their tissue or matrix. This method is essential in many areas of cell biology, regenerative medicine, and biomedical research. To create homogenous single-cell suspensions that may be further examined, grown, or used for a variety of downstream processes, cell dissociation procedures are utilized. The establishment of primary cell cultures typically uses cell dissociation. It permits the isolation and growth of cell types from tissues or organs, therefore establishing a regulated in vitro environment for investigating cell behavior, proliferation, differentiation, and responsiveness to diverse stimuli.
Dissociated cells can be used in tissue engineering techniques and cell-based therapeutics. Researchers may be able to replace harmed or diseased tissues with healthy cells by isolating cells from a donor source and preparing them for transplantation, thereby boosting tissue regeneration and repair. Dissociated cells can be utilized to test the toxicity and effectiveness of putative medicinal molecules throughout the drug discovery process. Researchers can assess different medications' or chemicals' effects on cell survival, proliferation, or certain biological activities by exposing dissociated cells to them.
Cell Dissociation Market Dynamics
The main factor fueling the industry's expansion is the increased emphasis on developing cell-based therapies. Market growth is being fueled by an increase in clinical studies, FDA approvals, and strategic moves by major companies. For instance, Sanofi and Innate Pharma SA increased their cooperation with Sanofi in December 2022 for natural killer cell treatments in cancer. A research cooperation and licensing agreement to market and develop up to four iPSC-derived initiatives for solid tumors and hematologic malignancies was also announced in September 2022 by Century Therapeutics and Bristol Myers Squibb.
Additionally, introducing novel items presents further lucrative chances within the anticipated period. For instance, LevitasBio introduced Optimized Tissue Dissociation Reagents in November 2021. The business's tissue dissociation kits are made specifically for the LeviCell processes and enable end-to-end handling of various human and model tissue types, including kidney, liver, lung, brain, tumor, and heart.
The kit allows users to maximize suspended cell viability while reducing cell damage, stress, or population bias. In addition, expanding government and corporate financing for stem cell research will probably present the sector with additional growth prospects. For instance, the California Institute for Regenerative Medicine awarded the City of Hope a grant for USD 4.9 million in March 2022. The grant will assist the research center in educating the subsequent generation of scientific luminaries in stem cell research and its application to novel, life-saving therapies. The awards will support laboratory work and help researchers develop cell-based medicines, create and manufacture cells, obtain regulatory approval, and market biomedical goods.
However, experiments on cell cultures call for an antiseptic environment, costly instruments, and qualified workers are major challenges in the market. Additionally, there are rarely any dissociated cells, which leads to an inadequate number of experiments. The abilities required to conduct an experiment include knowledge of the most recent research findings, a precise and thorough market analysis of a certain laboratory technique and its tools, and an introduction to novel concepts. The lack of trained workers hinders market expansion. Because neuronal cell lines respond to various physiological variables associated with neurotransmitters, managing such cell lines in neuronal cell culture calls for a specialist in the area to prevent contamination and harm to the cell lines.
Cell Dissociation Market Ecosystem
The global cell dissociation market is analyzed from the following perspectives by products, type, end user, and region.
Cell Dissociation Market by Product
Based on the product, the global cell dissociation market is segmented into enzymatic dissociation, non-enzymatic dissociation, instruments & accessories.
In 2022, the enzymatic dissociation segment led the global market and was responsible for more than 45.00% of total revenue. Enzymes are used to break down the fragments of tissue that were broken up, releasing the tissue's cells. The dissociation process makes use of a variety of enzymes, some of which can be combined. Mononuclear cell isolation from the spinal cord and brain is made easier and more successful by all enzymatic dissociations.
For instance, in June 2020, The FDA approved the use of collagenase injections to treat cellulite in adult females. The market is growing in this niche since it is readily available as an injection. Additionally, the isolated enzymes collagenase and hyaluronidase are effective in the treatment of breast cancer. Furthermore, the usage of collagenase is growing along with the frequency of glaucoma. For instance, according to a report, glaucoma affected more than 80 million individuals worldwide in 2022, with more than 3 million instances being documented in the United States alone.
The non-enzymatic segment is anticipated to see the highest CAGR growth during the forecast period. The formulation lacking enzymes helps maintain the structural and functional integrity of the cell surface proteins. It also has the advantage of avoiding the cytotoxic side effects of chelating drugs. Additionally, the usage of components originating from animals is subject to a growing amount of regulatory scrutiny throughout the production of biopharmaceuticals. Therefore, there is a need to provide non-enzymatic cell culture goods, which will spur sector expansion.
Cell Dissociation Market by Type
Based on the type, the global cell dissociation market is segmented into tissue dissociation and cell detachment.
In 2022, the tissue dissociation type segment led the global market and accounted for the most revenue, 53.50%. The market segment is anticipated to continue growing steadily while maintaining its leadership position globally. This market is expected to rise due to a result of factors including the biopharmaceutical and pharmaceutical industries' increased focus on the creation of monoclonal antibodies and the individualization of medical care. Cell detachment type, on the other hand, is predicted to develop at the fastest rate over the projection period. When cultivating adherent cells, cell dissociation is crucial. The most popular method of separation is trypsinization.
Cell Dissociation Market by End User
Based on the end user, the global cell dissociation market is segmented into biopharmaceutical and biotechnology companies, research & academic institutes.
The biopharmaceutical and biotechnology companies hold the highest market share as a result of their growing R&D expenditures in several therapeutic areas for the development of innovative medications. Additionally, funds have been allocated to more research projects, including toxicity studies, clinical trials, and efficacy studies. These factors fuel the need for dissociation products in the biopharmaceutical and biotechnology industries for the separation of cells from primary tissues.
Due to the safety and high effectiveness of these medications, prospects in the biopharmaceuticals sector have been growing over the past several years. Additionally, they provide a number of advantages, including powerful action and high efficacy, the possibility to treat the cause of an illness rather than just the symptoms, and fewer side effects, all of which have helped to fuel the growth in demand for biopharmaceutical products. The market in this category is also being driven by the growing R&D expenditure by biopharmaceutical companies.
Cell Dissociation Market by Region
Based on the region, the global cell dissociation market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
In 2022, North America dominated the market globally, accounting for a revenue share of 33.20%. The growth in government investment programs, the rise in the prevalence of chronic illnesses like cancer, and the availability of top-notch infrastructure for clinical and laboratory research in the region may all be credited to the region's high share. As an illustration, the Globocan report from 2020 states that there were around 612,390 fatalities and 2,281,658 new cancer cases in the United States. As a result, the market's growth possibilities are expanding due to the rising incidence of chronic and infectious illnesses as well as the growing emphasis on cell-based treatments.
The Asia Pacific region is predicted to expand at the fastest pace throughout the projection period due to the increasing need for innovative therapies. Other important elements driving the growth of the regional market include escalating government R&D expenditures and swift infrastructure development. Treatment for numerous chronic diseases, such as cancer, is also being developed by a number of local businesses with financing. For instance, Immuneel Therapeutics was given a budget of USD 15 million in June 2022 to provide cost-effective cell and gene therapy for cancer patients in India.
Cell Dissociation Market Competitive Landscape
Major firms are using various techniques, such as brand-new product releases, partnerships, collaborations, mergers & acquisitions, and regional expansions, to increase their market position. S2 Genomics, for instance, introduced the Singulator 100 System in February 2020. The System automates the conversion of solid tissue samples into high-yielding suspensions of nuclei or single cells from tiny samples for a wide variety of single-cell biology and genomic investigations. Some of the prominent market players in the global cell dissociation market include,
Cell Dissociation Market Strategic Development
Cell dissociation is the process of isolating individual cells or small cell clusters by removing them from their tissue or matrix. This method is essential in many areas of cell biology, regenerative medicine, and biomedical research.
North America is dominating the global cell dissociation market.
The estimated market size of the cell dissociation market in 2031 will be US$ 875.0 million.
The revenue CAGR of the cell dissociation market during the forecast period will be 12.2%.
Some of the major market players in the global cell dissociation market include Merck KGaA, Thermo Fisher Scientific, and Danaher Corp.
*Insights on financial performance are subject to the availability of information in the public domain