Bone Void Fillers Market
Number of pages: 100 | Report Format: PDF | Published date: February 01, 2023
Historical Years – 2020 | Base Year – 2021 | Forecasted Years – 2022-2030
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Report Attribute |
Details |
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Market Size value in 2021 |
US$ 3.27 billion |
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Revenue Forecast in 2030 |
US$ 5.81 billion |
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CAGR |
5.9% |
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Base Year For Estimation |
2021 |
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Forecast period |
2022-2030 |
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Historical Year |
2020 |
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Segments Covered |
Type, Form, End-user, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, and the Rest of the World (RoW) |
According to the deep-dive market assessment study by Growth Plus Reports, the global bone void fillers market was valued at US$ 3.27 billion in 2021 and is expected to register a revenue CAGR of 5.9% to reach US$ 5.81 billion by 2030.
Bone Void Fillers Market Fundamentals
A bone void is a hole that develops when the bone's natural mending process is interrupted. Trauma, infection, tumors, and side effects of joint replacements can all cause healthy bone tissue to be lost or destroyed. Bone voids are frequently caused due to trauma. A traumatic defect that is too large or where the bone fragments are spaced too far apart is not likely to heal properly.
Osteomyelitis is a bacterial infection of the bone tissue that can cause bone voids and is challenging to treat. It is frequently a complication of an underlying condition, such as a bone fixation operation following trauma, particularly if an open fracture is present. If osteomyelitis is not treated during the acute stage, it can develop chronically and destroy bones. Revision arthroplasty can potentially result in bone voids. Aseptic loosening and periprosthetic joint infections are two categories under which revision arthroplasty can be categorized. Both of these are potential side effects of joint replacement surgeries. Bone void fillers (BVF) are applied to the extremities, posterolateral spine, and pelvis to fill in holes and voids in the skeletal system. They are absorbable, biocompatible, bioactive, and osteoconductive biologic materials. For a range of orthopedic applications, the biological material aids bone regeneration by providing stability and encouraging cell proliferation.
Some common types of bone void fillers are:
Each type of bone void filler has its own advantages and disadvantages. For instance, PMMA is strong and durable; however, it can be difficult to remove if needed. HA is biocompatible and helps promote bone growth; however, it can be expensive. CS is inexpensive and easy to use; however, it may not be as strong as other options.
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Bone Void Fillers Market Dynamics
The growing prevalence of orthopedic diseases, such as osteoarthritis, bone tumors, and bone infections, is the major driving factor for the bone void fillers market revenue growth. The rise in road accidents and the increasing number of sports injuries due to the developing sports industry is playing a significant role in the revenue growth of the bone void fillers market. The increase in the number of joint replacement procedures is raising the possibility of osteomyelitis, a kind of bone infection. This is increasing the demand for drug-eluting bone fillers. Moreover, the growing R&D related to the bone void fillers to develop novel antibiotic drug-eluting bone fillers is propelling the growth of the bone void fillers market. Additionally, the increasing adoption of synthetic bone void fillers, due to the numerous benefits, such as lesser possibilities of morbidity, excessive sterility, and a high supply of synthetic materials, is fueling the global bone void fillers market revenue growth. Furthermore, the growing geriatric population, which is more prone to bone infections and fractures, and the increasing launch of products are anticipated to boost the bone void fillers market revenue growth in the next few years.
However, different risks associated with bone void fillers, such as infection at the site of the bone void filler injection, allergic reaction to the bone void filler material, and bleeding at the site of the injection, are likely to restrict the adoption of these fillers, which in turn, may hamper the revenue growth of the bone void fillers market.
Bone Void Fillers Market Ecosystem
The global bone void fillers market has been analyzed from four perspectives: type, form, end-user, and region.
Bone Void Fillers Market by Type
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Based on the type, the global bone void fillers market is segmented into demineralized bone matrix, collagen matrix, tri-calcium phosphate, calcium sulfate, and others.
The demineralized bone matrix segment dominated the bone void fillers market in 2021. This is ascribed to the greater biocompatibility of demineralized bone matrix and their ability to help in osteoconductive (stimulate new bone growth) and osteoinductive (encourage new bone formation) activities. The demineralized bone matrix reduces inflammation and pain and reduces the overall healing time. Moreover, the presence of a wide product portfolio and abundant donor sources are also expected to help in the segment revenue growth during the forecast period.
Bone Void Fillers Market by Form
Based on the form, the global bone void fillers market is segmented into gel, paste, granules, putty, and others.
The putty segment accounted for the largest revenue share of the bone void fillers market in 2021. Due to its form, putty is easier to use, allowing for a customized fit in the bone defect, and does not require any prior preparation before installation. The demand for demineralized bone matrix in the form of putty is projected to rise as bone disorders become more common, particularly in developing nations where demineralized bone matrix usage is higher than the other types. Moreover, a rise in product launches is propelling the segment revenue growth.
Bone Void Fillers Market by End-user
Based on the end-user, the global bone void fillers market is segmented into hospitals, specialty clinics, and others.
The hospitals segment accounted for a prominent revenue share of the bone void fillers market in 2021. One of the main drivers of the segment's revenue growth includes the rise in overall hospital visits, which can be attributed to increase in the need for post-operative care and the accessibility to qualified experts at hospitals. Additional factors fueling the market segment revenue growth include an increase in the hospitalization rate for patients suffering from orthopedic disorders and a wide range of services provided by hospitals in one place. Moreover, increase in the availability of favorable reimbursement policies at hospitals as compared to other end-users is helping the segment flourish.
Bone Void Fillers Market by Region
Based on the region, the global bone void fillers market has been segmented into North America, Europe, Asia Pacific, and the Rest of the World.
North America dominated the global bone void fillers market in 2021, followed by Europe and Asia Pacific. High adoption of synthetic bone void fillers and increased R&D in the region to develop new antibiotic bone void fillers are propelling the bone void fillers market revenue growth in North America. The region’s expanding sports business is generally leading to more sports injuries, which is driving up the demand for bone void fillers, thus driving the regional market expansion. Around 7 million sports-related injuries are reported each year in the United States, according to the Centers for Disease Control and Prevention (CDC). In addition, there is a rise in the number of fractures brought on by osteoporosis and musculoskeletal issues in North America. The target patient base is also steadily expanding due to an increase in traffic accidents, which is driving up the overall volume of orthopedic surgery and fostering regional market revenue growth. A strong healthcare infrastructure, the presence of major business players, and product launches are fueling the region’s revenue growth.
Bone Void Fillers Market Competitive Landscape
The prominent players operating in the global bone void fillers market are:
Bone Void Fillers Market Strategic Developments
BONESUPPORT AB, NuVasive Inc., Stryker Corporation, Collagen Matrix, Inc., and DePuy Synthes (Johnson & Johnson) are among the prominent players operating in the global market.
North America accounts for the largest market revenue share, followed by Europe; and Asia Pacific is the fastest-growing market region.
The global bone void fillers market is estimated to reach US$ 5.81 billion by 2030.
The demineralized bone matrix segment accounts for the largest revenue share of the global bone void fillers market.
The growing prevalence of orthopedic diseases, such as osteoarthritis, bone tumors, and bone infections, together with rising R&D in antibiotic bone void fillers, is driving the market revenue growth. The rising adoption of synthetic bone void fillers and the increased geriatric population are driving factors for the global market.
*Insights on financial performance are subject to the availability of information in the public domain