Biological Skin Substitutes Market
Number of pages: 100 | Report Format: PDF | Published date: February 27, 2023
Historical Years – 2020 | Base Year – 2021 | Forecasted Years – 2022-2030
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Report Attribute |
Details |
|
Market Size Value in 2021 |
US$ 1.5 billion |
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Revenue Forecast in 2030 |
US$ 4.19 billion |
|
CAGR |
11.75% |
|
Base Year for Estimation |
2021 |
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Forecast Period |
2022-2030 |
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Historical Year |
2020 |
|
Segments Covered |
Product Type, Application, End Use, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, and the Rest of the World (RoW) |
According to the deep-dive market assessment study by Growth Plus Reports, the global biological skin substitutes market was valued at US$ 1.5 billion in 2021 and is expected to register a revenue CAGR of 11.75% to reach US$ 4.19 billion by 2030.
Biological Skin Substitutes Market Fundamentals
Biological skin substitutes are natural, synthetic, or biosynthetic materials used to cover large wounds in order to restore skin functions. Biological skin substitutes help to close wounds temporarily or permanently, which prevents them from infection, additional damage, and water loss and alleviates discomfort. Additionally, they aid in the regeneration of normal skin over the wound.
Biological skin substitutes are made up of an exterior epidermal layer or dermal layer contained in an acellular matrix (a support structure). The substitutes have the benefit of being relatively readily accessible and acting momentarily like real skin. The extracellular matrix structure of the biological skin substitutes is more intact and native, which would make it possible to develop a new dermis that is more resemblant to the original one. These substitutes also have good re-epithelialization properties due to the presence of a basement membrane, which provides a physical barrier to bacteria and makes biological substitutes an ideal choice for tissue repair. The major application of biological skin substitutes is in treating chronic ulcers, blistering diseases, burns, and postsurgical wounds. The most used biological skin substitutes are cadaveric skin allografts, porcine skin xenografts, amnion, chemical injuries, and cultured epithelial autografts.
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Biological Skin Substitutes Market Dynamics
The global biological skin substitutes market is predicted to develop at significant revenue CAGR during the forecast period, due to its great application in burn wound care and chronic wound care. Biological substitutes are becoming a more crucial component of the burn treatment plan. These substitutes improve functional and aesthetic results over time during the acute phase of burn therapy, hence raising the quality of life. Moreover, these substitutes allow physicians to treat severe cases and enhance patient survival rates and quality of life. Furthermore, increasing research and development activities are resulting in the introduction of innovative biological skin substitutes for burn wound treatment. The demand for biological skin substitutes in treating chronic wounds is attributed to their effective results in treating the wound. Treatment with biological skin substitutes can help in quick recovery resulting in fewer infections and scars. Moreover, as the incidences of chronic wounds are highly increasing, the demand for more advanced biological skin substitutes is also increasing.
The most recent advancement in the biological skin substitutes market is the availability of polymeric alternatives that are combined with pharmacological and antibacterial agents to boost healing or regeneration processes. Biodegradable polymers are extremely useful in biomedical applications since they allow for the degradation of the original, functioning tissue as a part of the healing process.
The rise in awareness about biological skin substitutes is a potential factor fueling the biological skin substitutes market revenue share. For instance, in January 2023, Southeastern Wound Healing Centre, a UNC Health Southeastern subsidiary run by Healogics LLC, announced the Come Heal With US campaign. The campaign is aimed at spreading awareness about sophisticated medical care for complex wounds. The center provides comprehensive wound care and cutting-edge treatments, such as growth factor therapy, negative pressure wound therapy, biological skin replacement, and dressings made of biological and synthetic materials.
However, the limited awareness and low accessibility to skin substitutes in low-income countries are the major factors hindering the revenue growth of the global biological skin substitutes market.
Biological Skin Substitutes Market Ecosystem
The global biological skin substitutes market has been analyzed from four perspectives: product type, application, end user, and region.
Biological Skin Substitutes Market by Product Type
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Based on product type, the global biological skin substitutes market has been segmented into human donor tissue-derived products, biosynthetic products, and animal-derived products.
The human donor tissue-derived products and animal-derived products segments are expected to show steady revenue growth during the forecast period, owing to their traditional usage. The human-derived products segment is sub-segmented into allografts, amnion, and cultured epithelial autografts (CEA). The allografts sub-segment accounts for the highest revenue share owing to the benefits it offers in burn wound management, such as being a cost-effective biological substitute and the ability to reduce pain and risk of infections. Moreover, allografts-derived biological skin substitutes decrease frequent dressing changes.
The biosynthetic products segment is further segmented into collagen and polyglactin. The biosynthetic products segment is expected to show a high revenue share in the forecast years due to several advantages. Biosynthetic skin substitutes are a cost-effective alternative to traditional skin grafts, as they require fewer resources to produce. These skin substitutes are biocompatible to the human body. Moreover, biosynthetic skin substitutes are more durable than traditional skin grafts, making them a more reliable long-term solution.
Biological Skin Substitutes Market by Application
Based on application, the global biological skin substitutes market has been segmented into acute wounds and chronic wounds.
The acute wounds segment accounted for the largest biological skin substitutes market revenue share in 2021. The acute wound segment is further sub-segmented into surgery and trauma & burns. The burns segment accounted for the largest market revenue share. Skin substitutes are an effective treatment in burn wound management, as they provide structural support and accelerate healing while also reducing the risk of infection. Moreover, It has been demonstrated via research that a variety of biological skin substitutes can be helpful in the treatment of partial and full-thickness burns. They are efficient, accelerate wound healing, and shorten hospital stays.
Biological Skin Substitutes Market by End User
Based on end user, the global biological skin substitutes market has been segmented into hospitals, home healthcare, wound care centers, and others.
The hospitals segment accounted for the largest revenue share in 2021. This is due to better accessibility to biological skin substitutes that hospitals provide, such as artificial skin, to help treat burn victims and other skin-related issues. This is due to proper care management in hospitals. Moreover, the hospitals segment is gaining traction owing to higher patient preference due to the presence of skilled management and the presence of reimbursement policies in hospitals.
Biological Skin Substitutes Market by Region
Based on the region, the global biological skin substitutes market has been segmented into North America, Europe, Asia Pacific, and the Rest of the World.
North America leads the global biological skin substitutes market due to increasing demand for products that can offer more natural results and the growing awareness of the benefits of biological skin substitutes. Furthermore, advances in technology have made it possible for more advanced skin substitutes to be produced. Additionally, there has been an increase in the number of clinical trials conducted on the efficacy of these products. Moreover, the rising number of patients undergoing skin transplants and the increasing number of skin disorders in the region are also contributing to the revenue growth of the market.
Asia Pacific is anticipated to show high revenue growth during the forecast period. The region’s high per capita income and rise in awareness of biological skin substitutes are key factors supporting the biological skin substitutes market revenue share in Asia Pacific. Additionally, governments in the region are highly interested in advancing their healthcare settings with more technologically advanced treatments, hence increasing the biological skin substitutes market revenue growth.
Biological Skin Substitutes Market Competitive Landscape
The prominent players in the global biological skin substitutes market include:
The high adoption of biological skin substitutes in burn, trauma, and chronic wound cases is the most prominent trend in the global biological skin substitutes market.
Organogenesis, Inc., Integra LifeSciences Corporation, Smith and Nephew plc, and Mimdex Group are among the top players in the market.
The human donor tissue-derived products segment is expected to grow rapidly in the coming years.
Asia Pacific is expected to mark the highest revenue growth during the forecast period.
The high cost of products and stringent regulations are the most prominent restraints in the global biological skin substitutes market.
*Insights on financial performance are subject to the availability of information in the public domain