Increasing application of HPLC in drug development owing to its high precision and accuracy is expected to elevate the growth of HPLC market

High-performance Liquid Chromatography (HPLC) Market by Product Type (Instruments, Consumables, and Accessories), Application (Pharmaceuticals and Biotechnology industries, Forensics, Food & Beverage industries, and Diagnostics)–Global Outlook & Forecast 2022-2030

According to the deep-dive market assessment study conducted by Growth + Reports, the global high-performance liquid chromatography (HPLC) market was pegged at ~US$ 4.7 billion in 2021. The market is expected to witness a CAGR of ~4.4% from 2022 to 2030.

Factors contributing to the growth of the global HPLC market include advantages of the HPLC technique such as higher precision and accuracy. Moreover, factors such as the increasing use of HPLC in drug development and approval and technological advancements are some of the other factors playing a pivotal role in driving the growth of the HPLC market. Growing application of HPLC techniques in discovery and development of monoclonal antibodies has proved another driving factor for global HPLC market. However, lack of qualified specialists and the high cost of equipment are expected to limit market expansion to some extent, especially in developing countries.

Analytical testing plays a critical role in the drug development as well as drug approval process in the pharmaceutical company. HPLC is one of the major analytical tools used for quality assurance and drug monitoring. As HPLC is specific, rapid, and accurate, many pharmaceutical companies now almost exclusively use HPLC as a chromatographic technique. Thus, increasing use of HPLC in drug development coupled with the rising R&D activities in the pharmaceutical industry is driving the growth of this market.

The use of hyphenated techniques is rising as they help to explore advantages of each of the individual techniques. HPLC is coupled with UV and mass spectroscopy for screening of natural products. Studies have shown that the use of hyphenated technologies have proven to be extremely powerful tools in product analysis as they help in rapid determination of known substances with only a small amount of source material. Such factors have led to rising use of hyphenated techniques and in turn boost the HPLC market.

The prominent players in the HPLC market are focusing on developing new and advanced systems and launching them in the market. For instance, in November 2020, Shimadzu Corporation launched new “Advanced i-Series” High Performance Liquid Chromatography (LC-2050 model) domestically and overseas. Similarly, in June 2020, Waters launched new Arc HPLC system for routine quality control testing in the pharmaceutical, food, academic, and materials markets.

Monoclonal antibodies holds a large share of the HPLC market. Monoclonal antibodies (mAbs) are highly complex recombinant proteins used successfully as therapeutics in many disease indications. Numerous analytical techniques are required to characterize and control the quality of these molecules during their clinical development and commercial production. Thus, this segment is boosting the HPLC market.

However, as the cost for developing HPLC process is quite higher, use of HPLC is not feasible at small and private settings. Moreover, dearth of skilled technicians to handle these instruments is also hindering the market growth to a certain extent.

Regionally, Asia Pacific is anticipated to be the fastest-growing region in the HPLC market during the forecast period. Factors attributing to the growth of the HPLC market in this region include the rising number of R&D activities, rising government support for R&D, and the surging number of new pharma and biotech companies. The Indian pharmaceutical and CROs market is expanding at a tremendous rate. This results in an increase in the number of quality control, method development, research, and drug discovery laboratories. This is a driving factor for the HPLC market. Likewise, China has observed explosive growth in the HPLC market because of the Chinese government’s massive investment in the domestic infrastructure development.

Some of the prominent players operating in the global HPLC market include Agilent Technologies Inc., Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Waters Corporation, Shimadzu Corporation, PerkinElmer Inc., Hitachi High-Technologies Corporation, Merck KGaA, Tosoh Bioscence LLC, Danaher Corporation among others.

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