Increased competition in therapeutics and greater prevalence of large molecule drugs are expected to play a pivotal role in driving the growth of liquid chromatography market

Global Liquid Chromatography Market by Type (Instruments, Consumables, Software & Accessories), Technique ((High-Pressure Liquid Chromatography (HPLC), Normal Phase Liquid Chromatography (NPLC), Ion Exchange Liquid Chromatography (IELC), Size Exclusion Liquid Chromatography (SELC), Fast Protein Liquid Chromatography (FPLC), Reverse phase Liquid Chromatography (RPLC)), End-User (Pharmaceutical & Biotechnology industries, Food & Beverage industries, Forensics, Diagnostic laboratories) – Global Outlook & Forecast 2022-2030

According to the deep-dive market assessment study conducted by growth plus reports, the global liquid chromatography market was pegged at US$ 9.7 Billion in 2021. The market is expected to witness a CAGR of 5.4% from 2022 to 2030.

The global liquid chromatography market has been experiencing growth due to the following driver such as increasing demand for biologics, due to which many biopharmaceuticals have started taking initiatives to characterize the compounds. Certain additives are added to food to maintain its freshness and flavor. However, these chemicals pose threat to health, it is important to keep an eye on the quantity for which liquid chromatography techniques are used intensively. Further, Increased investments by research users and government bodies would further increase the usage of liquid chromatography techniques, and gradually drive the growth of the global liquid chromatography market during the forecast period.

Increased competition in therapeutics, greater prevalence of large molecule drugs, and expansion in the number of products have given rise to the biopharmaceuticals market which is directly responsible for driving the market. Evolution in the technology and processes in the biopharma segment also drives the global liquid chromatography market. According to a report by Statista, 2020, the biopharmaceutical market size is around US$ 300 billion and this is expected to increase to nearly one trillion by 2030. Additionally, many monoclonal antibodies have been designed over the years for the treatment of immunologic diseases and cancer therapy. For characterization and identification purposes, liquid chromatography is extensively used as a mode of separation of these monoclonal antibodies.

Food safety is a major global concern. According to the World Health Organization, 2022 factsheet, an estimated 600 million – almost 1 in 10 people in the world – fall ill due to food

contamination, and 4,20.000 die every year, resulting in the loss of 33 million healthy life years (DALYs). Thus, improved methods for the determination of authenticity, standardization, and efficacy of nutritional properties in natural food products are required to guarantee food quality. The Food Additives Amendment of 1958 made the FDA responsible for regulating food additives. So, food companies are using chromatography to separate mixtures and identify additives, as proof to show that they are meeting the regulations. Liquid chromatography is used as a powerful analytical technique to identify or separate complex compounds in food.

Over the years, there have been a significant investments made by key players in R&D activities and increased government funding in disease-related research. This factor increased the new scope to develop novel technologies in the field of chromatography, hence propelling the global liquid chromatography market.

However, the presence of many alternative techniques like Protein crystallization, membrane chromatography, crystallization, high-resolution extra filtration, three-phase partition monolith, capillary electrophoresis, precipitation, and high-pressure folding are expected to challenge the liquid chromatography equipment market. Also, the high cost of the liquid chromatography market has a negative impact on the market.

North America is expected to be a major market for liquid chromatography. Increased direct and indirect investments by the U.S government and market key players in chromatography have attributed to the rapid growth of the liquid chromatography market in North America. A rise in investments might bring about the improvement of the latest technology that could appeal to greater customers, thereby riding the marketplace. Moreover, big studies and improved activities within the U.S. needs excessive usage of liquid chromatography systems.Stringent guidelines for drug approval in North America require evaluation of the medicine and the usage of liquid chromatography techniques. This aspect is predicted to propel the marketplace growth.

Some of the prominent players operating in the liquid chromatography market are Waters Corporation, Tosoh bioscience LLC, Hitachi Ltd., PerkinElmer, Inc., Thermo Fisher Scientific., Shimadzu Corporation, Agilent Technologies, and Merck KGaA among others.

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